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Introduction
Symptomatic management is the main focus of ALS clinical care. We aim to report the prevalence of ALS‐related symptoms and characterize self‐reported symptomatic management.
Methods
A symptom management survey developed by the Muscular Dystrophy Association Clinical Research Network was completed by ALS registrants. Logistic regression identified potential predictors of symptom prevalence,...
Introduction: The pathology of amyotrophic lateral sclerosis (ALS) is associated with impaired RNA processing and microRNA (miRNA) dysregulation. Here we investigate the regulation of the members of the miRNA biogenesis pathways and total miRNA levels at different stages of the disease. Methods: Muscle, brain, and spinal cord tissue were obtained from presymptomatic, symptomatic, and end‐stage superoxide...
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