Magnetic Resonance in Medicine

Items from 1 to 20 out of 239 results

article

Optimization of pseudo‐continuous arterial spin labeling at 7T with parallel transmission B1 shimming

Kai Wang, Samantha J. Ma, Xingfeng Shao, Chenyang Zhao, more

Magnetic Resonance in Medicine > 87 > 1 > 249 - 262

Purpose To optimize pseudo‐continuous arterial spin labeling (pCASL) for 7 T, and to further improve the labeling efficiency with parallel RF transmission transmit B₁ (

B_{1}^{+}

) shimming. Methods pCASL parameters were optimized based on

B_{1}^{+} / B_{0}

field distributions at 7 T with simulation. To increase labeling efficiency, the

B_{1}^{+}

amplitude at inflowing arteries was increased with parallel RF transmission...

article

Free‐breathing MR elastography of the lungs: An in vivo study

Faisal Fakhouri, Stephan Kannengiesser, Josef Pfeuffer, Yevgeniya Gokun, more

Magnetic Resonance in Medicine > 87 > 1 > 236 - 248

Purpose Lung stiffness alters with many diseases; therefore, several MR elastography (MRE) studies were performed earlier to investigate the stiffness of the right lung during breathhold at residual volume and total lung capacity. The aims of this study were 1) to estimate shear stiffness of the lungs using MRE under free breathing and demonstrate the measurements’ repeatability and reproducibility,...

article

Assessment of the effects of mimicking tissue microstructural properties on apparent diffusion coefficient and apparent exchange rate in diffusion MRI via a series of specially designed phantoms

Xiaodong Li, Yafei Bai, Yupeng Liao, Sherman Xuegang Xin

Magnetic Resonance in Medicine > 87 > 1 > 292 - 301

Purpose Diffusion MRI provides a valuable tool for imaging tissue microstructure. However, due to the lack of related experimental methods and specially designed phantoms, no experimental study has been conducted yet to quantitatively assess the effects of membrane permeability, intracellular volume fraction (IVF), and intracellular diffusivity on the apparent diffusion coefficient (ADC) obtained...

article

An MR fingerprinting approach for quantitative inhomogeneous magnetization transfer imaging

Daniel J. West, Gastao Cruz, Rui P. A. G. Teixeira, Torben Schneider, more

Magnetic Resonance in Medicine > 87 > 1 > 220 - 235

Purpose Magnetization transfer (MT) and inhomogeneous MT (ihMT) contrasts are used in MRI to provide information about macromolecular tissue content. In particular, MT is sensitive to macromolecules, and ihMT appears to be specific to myelinated tissue. This study proposes a technique to characterize MT and ihMT properties from a single acquisition, producing both semiquantitative contrast ratios...

article

Magnetic microspheres can be used for magnetic particle imaging of cancer cells arrested in the mouse brain

Kierstin P. Melo, Ashley V. Makela, Natasha N. Knier, Amanda M. Hamilton, more

Magnetic Resonance in Medicine > 87 > 1 > 312 - 322

Purpose Magnetic particle imaging (MPI) is a new imaging modality that sensitively and specifically detects superparamagnetic iron oxide nanoparticles (SPIOs). MRI cell tracking with SPIOs has very high sensitivity, but low specificity and quantification is difficult. MPI could overcome these limitations. There are no reports of micron‐sized iron oxide particles (MPIO) for cell tracking by MPI. Therefore,...

article

The Coax Dipole: A fully flexible coaxial cable dipole antenna with flattened current distribution for body imaging at 7 Tesla

Carel C. van Leeuwen, Bart R. Steensma, Dennis W. J. Klomp, Cornelis A. T. van den Berg, more

Magnetic Resonance in Medicine > 87 > 1 > 528 - 540

Purpose The coax dipole antenna, a flexible antenna for body imaging at 7T is presented. Similar to the high impedance coil, this coaxial cable antenna is fed on the central conductor and through gaps in the shield, the current passes to the outside of the antenna to generate B₁ field. This could achieve more favorable current distributions and better adaptation to the body curvature. Methods Finite...

article

Multiparametric mapping in the brain from conventional contrast‐weighted images using deep learning

Shihan Qiu, Yuhua Chen, Sen Ma, Zhaoyang Fan, more

Magnetic Resonance in Medicine > 87 > 1 > 488 - 495

Purpose To develop a deep‐learning–based method to quantify multiple parameters in the brain from conventional contrast‐weighted images. Methods Eighteen subjects were imaged using an MR Multitasking sequence to generate reference T₁ and T₂ maps in the brain. Conventional contrast‐weighted images consisting of T₁ MPRAGE, T₁ GRE, and T₂ FLAIR were acquired as input images. A U‐Net–based neural network...

article

A Huygens’ surface approach to rapid characterization of peripheral nerve stimulation

Mathias Davids, Bastien Guerin, Lawrence L. Wald

Magnetic Resonance in Medicine > 87 > 1 > 377 - 393

Purpose Peripheral nerve stimulation (PNS) modeling has a potential role in designing and operating MRI gradient coils but requires computationally demanding simulations of electromagnetic fields and neural responses. We demonstrate compression of an electromagnetic and neurodynamic model into a single versatile PNS matrix (P‐matrix) defined on an intermediary Huygens’ surface to allow fast PNS characterization...

article

Streaking artifact suppression of quantitative susceptibility mapping reconstructions via L1‐norm data fidelity optimization (L1‐QSM)

Carlos Milovic, Mathias Lambert, Christian Langkammer, Kristian Bredies, more

Magnetic Resonance in Medicine > 87 > 1 > 457 - 473

Purpose The presence of dipole‐inconsistent data due to substantial noise or artifacts causes streaking artifacts in quantitative susceptibility mapping (QSM) reconstructions. Often used Bayesian approaches rely on regularizers, which in turn yield reduced sharpness. To overcome this problem, we present a novel L1‐norm data fidelity approach that is robust with respect to outliers, and therefore...

article

Relaxation‐corrected macromolecular model enables determination of ¹H longitudinal T₁‐relaxation times and concentrations of human brain metabolites at 9.4T

Andrew Martin Wright, Saipavitra Murali‐Manohar, Tamas Borbath, Nikolai I. Avdievich, more

Magnetic Resonance in Medicine > 87 > 1 > 33 - 49

Purpose Ultrahigh field MRS has improved characterization of the neurochemical profile. To compare results obtained at 9.4T to those from lower field strengths, it is of interest to quantify the concentrations of metabolites measured. Thus, measuring T₁‐relaxation times is necessary to correct for T₁‐weighting that occurs in acquisitions for single‐voxel spectroscopy and spectroscopic imaging. A...

article

Magnetic resonance conditionality of abandoned leads from active implantable medical devices at 1.5 T

Yu Wang, Ran Guo, Wei Hu, Jianfeng Zheng, more

Magnetic Resonance in Medicine > 87 > 1 > 394 - 408

Purpose During MR scans, abandoned leads from active implantable medical devices (AIMDs) can experience excessive heating at the lead tip, depending on the type of termination applied to the proximal contacts (proximal end treatment). The influence of different proximal end treatments (ie, [1] freely exposed in the tissue, [2] terminated with metal in contact with the tissue, or [3] capped with plastic,...

article

Clinical translation of hyperpolarized ¹³C pyruvate and urea MRI for simultaneous metabolic and perfusion imaging

Hecong Qin, Shuyu Tang, Andrew M. Riselli, Robert A. Bok, more

Magnetic Resonance in Medicine > 87 > 1 > 138 - 149

Purpose The combined hyperpolarized (HP) ¹³C pyruvate and urea MRI has provided a simultaneous assessment of glycolytic metabolism and tissue perfusion for improved cancer diagnosis and therapeutic evaluation in preclinical studies. This work aims to translate this dual‐probe HP imaging technique to clinical research. Methods A co‐polarization system was developed where [1‐¹³C]pyruvic acid (PA)...

article

Role of chemical exchange on the relayed nuclear Overhauser enhancement signal in saturation transfer MRI

Tao Jin, Seong‐Gi Kim

Magnetic Resonance in Medicine > 87 > 1 > 365 - 376

Purpose The pH sensitivity of chemical exchange‐relayed nuclear Overhauser enhancement (rNOE) signal in a saturation transfer experiment is not fully understood and needs further investigation. Methods A three‐pool‐exchange model was simulated assuming that the magnetization transfer between an NOE pool and water is relayed by a chemical exchange (CE) pool. The saturation transfer signals from...

article

Validation of the estimation of the macrovascular contribution in multi‐timepoint arterial spin labeling MRI using a 2‐component kinetic model

Merlijn C. E. Plas, Martin Craig, Sophie Schmid, Michael A. Chappell, more

Magnetic Resonance in Medicine > 87 > 1 > 85 - 101

Purpose In this paper, the ability to quantify cerebral blood flow by arterial spin labeling (ASL) was studied by investigating the separation of the macrovascular and tissue component using a 2‐component model. Underlying assumptions of this model, especially the inclusion of dispersion in the analysis, were studied, as well as the temporal resolution of the ASL datasets. Methods Four different...

article

Remodeling after myocardial infarction and effects of heart failure treatment investigated by hyperpolarized [1‐¹³C]pyruvate magnetic resonance spectroscopy

Rasmus Stilling Tougaard, Christoffer Laustsen, Thomas Ravn Lassen, Haiyun Qi, more

Magnetic Resonance in Medicine > 87 > 1 > 57 - 69

Purpose Hyperpolarized [1‐¹³C]pyruvate MRS can measure cardiac metabolism in vivo. We investigated whether [1‐¹³C]pyruvate MRS could predict left ventricular remodeling following myocardial infarction (MI), long‐term left ventricular effects of heart failure medication, and could identify responders to treatment. Methods Thirty‐five rats were scanned with hyperpolarized [1‐¹³C]pyruvate MRS 3 days...

article

Motion‐robust quantitative multiparametric brain MRI with motion‐resolved MR multitasking

Sen Ma, Nan Wang, Yibin Xie, Zhaoyang Fan, more

Magnetic Resonance in Medicine > 87 > 1 > 102 - 119

Purpose To address head motion in brain MRI with a novel motion‐resolved imaging framework, with application to motion‐robust quantitative multiparametric mapping. Methods MR multitasking conceptualizes the underlying multiparametric image in the presence of motion as a multidimensional low‐rank tensor. By incorporating a motion‐state dimension into the parameter dimensions and introducing unsupervised...

article

Mono‐planar T‐Hex: Speed and flexibility for high‐resolution 3D imaging

Maria Engel, Lars Kasper, Bertram Wilm, Benjamin Dietrich, more

Magnetic Resonance in Medicine > 87 > 1 > 272 - 280

Purpose The aim of this work is the reconciliation of high spatial and temporal resolution for MRI. For this purpose, a novel sampling strategy for 3D encoding is proposed, which provides flexible k‐space segmentation along with uniform sampling density and benign filtering effects related to signal decay. Methods For time‐critical MRI applications such as functional MRI (fMRI), 3D k‐space is usually...

article

Manifold‐based respiratory phase estimation enables motion and distortion correction of free‐breathing cardiac diffusion tensor MRI

Jaume Coll‐Font, Shi Chen, Robert Eder, Yiling Fang, more

Magnetic Resonance in Medicine > 87 > 1 > 474 - 487

Purpose For in vivo cardiac DTI, breathing motion and B₀ field inhomogeneities produce misalignment and geometric distortion in diffusion‐weighted (DW) images acquired with conventional single‐shot EPI. We propose using a dimensionality reduction method to retrospectively estimate the respiratory phase of DW images and facilitate both distortion correction (DisCo) and motion compensation. Methods...

article

In vivo spectral editing of phosphorylethanolamine

Steve C. N. Hui, Helge J. Zöllner, Georg Oeltzschner, Richard A. E. Edden, more

Magnetic Resonance in Medicine > 87 > 1 > 50 - 56

Purpose To demonstrate J‐difference editing of phosphorylethanolamine (PE) with chemical shifts at 3.22 (PE_3.22) and 3.98 (PE_3.98) ppm, and compare the merits of two editing strategies. Methods Density‐matrix simulations of MEGA‐PRESS (Mescher‐Garwood PRESS) for PE were performed at TEs ranging from 80 to 200 ms in steps of 2 ms, applying 20‐ms editing pulses (ON/OFF) at (1) 3.98/7.5 ppm to detect...

article

Minimal artifact actively shimmed metallic needles in MRI

Saikat Sengupta, Xinqiang Yan, Tamarya L. Hoyt, Gary Drake, more

Magnetic Resonance in Medicine > 87 > 1 > 541 - 550

Purpose Signal voids caused by metallic needles pose visualization and monitoring challenges in many MRI applications. In this work, we explore a solution to this problem in the form of an active shim insert that fits inside a needle and corrects the field disturbance (ΔB₀) caused by the needle outside of it. Methods The ΔB₀ induced by a 4 mm outside‐diameter titanium needle at 3T is modeled and...

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DEEP LEARNING (18)
BRAIN (13)
MRI (10)
QUANTITATIVE MRI (9)
ARTERIAL SPIN LABELING (7)
MAGNETIZATION TRANSFER (7)
MAGNETIC RESONANCE IMAGING (6)
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T1 MAPPING (6)
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DWI (5)
FMRI (5)
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QSM (5)
T2 MAPPING (5)
4D FLOW MRI (4)
CEREBROSPINAL FLUID (4)
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CHEMICAL EXCHANGE SATURATION TRANSFER (CEST) (4)
ECHO PLANAR IMAGING (4)
MACHINE LEARNING (4)
MR FINGERPRINTING (4)
MR MULTITASKING (4)
MRS (4)
MULTIPARAMETRIC MAPPING (4)
QUANTIFICATION (4)
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RF HEATING (4)
UNIVERSAL PULSE (4)
WHITE MATTER (4)
7T (3)
CEST (3)
CONVOLUTIONAL NEURAL NETWORKS (3)
DIFFUSION (3)
EPI (3)
FIELD MONITORING (3)
FREE‐BREATHING (3)
FUNCTIONAL MRI (3)
HUMAN BRAIN (3)
INTERVENTIONAL MRI (3)
LIVER (3)
LOW RANK (3)
MAGNETIC RESONANCE FINGERPRINTING (3)
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MEGA‐PRESS (3)
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PERFUSION (3)
PERIPHERAL NERVE STIMULATION (3)
PHASE‐CONTRAST MRI (3)
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RELAXATION (3)
RELAXOMETRY (3)
RF SAFETY (3)
SAFETY (3)
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1H MRS (2)
2D RF PULSE (2)
3T (2)
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AMIDE (2)
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APT (2)
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BODY MRI (2)
BOLD (2)
BRAIN MRI (2)
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DENOISING (2)
DIFFUSION‐WEIGHTED IMAGING (2)
DISTORTION CORRECTION (2)
DYNAMIC NUCLEAR POLARIZATION (2)
ELECTRICAL PROPERTIES TOMOGRAPHY (2)
FAT (2)
GLYMPHATIC SYSTEM (2)
HEART (2)
HEMORRHAGE (2)
HYPERPOLARIZATION (2)
HYPERPOLARIZED 129XE (2)
HYPERPOLARIZED PYRUVATE (2)
IHMT (2)
IHMT T1D‐FILTERING (2)
IMPLANT SAFETY (2)
INTERSTITIAL FLUID (2)
INTRACRANIAL (2)
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Magnetic Resonance in Medicine

Optimization of pseudo‐continuous arterial spin labeling at 7T with parallel transmission B1 shimming

Free‐breathing MR elastography of the lungs: An in vivo study

Assessment of the effects of mimicking tissue microstructural properties on apparent diffusion coefficient and apparent exchange rate in diffusion MRI via a series of specially designed phantoms

An MR fingerprinting approach for quantitative inhomogeneous magnetization transfer imaging

Magnetic microspheres can be used for magnetic particle imaging of cancer cells arrested in the mouse brain

The Coax Dipole: A fully flexible coaxial cable dipole antenna with flattened current distribution for body imaging at 7 Tesla

Multiparametric mapping in the brain from conventional contrast‐weighted images using deep learning

A Huygens’ surface approach to rapid characterization of peripheral nerve stimulation

Streaking artifact suppression of quantitative susceptibility mapping reconstructions via L1‐norm data fidelity optimization (L1‐QSM)

Relaxation‐corrected macromolecular model enables determination of ¹H longitudinal T₁‐relaxation times and concentrations of human brain metabolites at 9.4T

Magnetic resonance conditionality of abandoned leads from active implantable medical devices at 1.5 T

Clinical translation of hyperpolarized ¹³C pyruvate and urea MRI for simultaneous metabolic and perfusion imaging

Role of chemical exchange on the relayed nuclear Overhauser enhancement signal in saturation transfer MRI

Validation of the estimation of the macrovascular contribution in multi‐timepoint arterial spin labeling MRI using a 2‐component kinetic model

Remodeling after myocardial infarction and effects of heart failure treatment investigated by hyperpolarized [1‐¹³C]pyruvate magnetic resonance spectroscopy

Motion‐robust quantitative multiparametric brain MRI with motion‐resolved MR multitasking

Mono‐planar T‐Hex: Speed and flexibility for high‐resolution 3D imaging

Manifold‐based respiratory phase estimation enables motion and distortion correction of free‐breathing cardiac diffusion tensor MRI

In vivo spectral editing of phosphorylethanolamine

Minimal artifact actively shimmed metallic needles in MRI

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