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BACKGROUND
Outcomes projects can be a catalyst for determining disease‐ and treatment‐related consequences for patients with rare tumors. The Adult Ependymoma Outcomes (AEO) survey uses self‐reported experience to evaluate how this tumor affects patient groups throughout the illness trajectory.
METHODS
Patients completed the AEO survey via a Web‐based portal. The survey included questions on treatment,...
Medulloblastoma, the most common malignant brain tumor of childhood, occurs in the posterior fossa, the part of the intracranial cavity that contains the brainstem and the cerebellum. The cerebellum is involved in many complex aspects of human behavior and function, and when it is disrupted or insulted, this can lead to significant sequelae in children with posterior fossa tumors. A constellation...
BACKGROUND
American Indian and Alaska Native (AI/AN) breast cancer survivors experience disparities in breast cancer incidence and age‐adjusted mortality compared with non‐Hispanic white (NHW) breast cancer survivors. In addition, mortality‐to‐incidence rates indicate that AI/ANs continue to have the poorest survival from breast cancer compared with other racial groups. “Native American Cancer Education...
BACKGROUND
Physical activity (PA) has been linked to a lower risk of developing and dying of cancer, yet many cancer survivors do not exercise. In the current study, the authors evaluated the impact of the LIVESTRONG at the YMCA exercise program, available at Young Men's Christian Associations (YMCAs) across the United States, on PA, fitness, quality of life, fatigue, body composition, serum biomarkers,...
BACKGROUND
Sexual behavior and oral human papillomavirus (HPV) infection are risk factors for oral squamous cell carcinoma (OSCC). The effects of OSCC diagnosis and treatment on subsequent relationship stress and sexual behavior are unknown.
METHODS
Incident cases of HPV‐positive or HPV‐negative OSCC in patients who had a partnered relationship and partners of patients with oropharyngeal cancer...
BACKGROUND
The objective of this study was to describe perceptions and associated risk factors of the impact of cancer on functional outcomes, including social relationships, exercise, finances, and religion, among adult survivors of childhood cancer.
METHODS
Evaluable participants included 3001 adult survivors (mean age, 32.5 years; range, 18.3‐63.8 years; 24.1 years from diagnosis; 50.8% male;...
BACKGROUND
Breast cancer survivors face a risk of disease recurrence and a higher risk of developing comorbidities such as cardiovascular disease when compared with the general population. Physical activity (PA) has been shown to reduce such risks. The current analyses sought to identify: 1) unique patterns of PA among breast cancer survivors; and 2) characteristics associated with the level of PA...
BACKGROUND
Patients with prostate cancer and their providers face uncertainty as they consider adjuvant radiotherapy (ART) or salvage radiotherapy (SRT) after undergoing radical prostatectomy. The authors prospectively evaluated the impact of the Decipher test, which predicts metastasis risk after radical prostatectomy, on decision making for ART and SRT.
METHODS
A total of 150 patients who were...
BACKGROUND
Published studies have suggested that most patients with early stage breast cancer are willing, for modest survival benefits, to receive 6 months of adjuvant cyclophosphamide, methotrexate, and 5‐fluorouracil, an older regimen that is used infrequently today. We examined preferences regarding the survival benefit needed to justify 6 months of a contemporary chemotherapy regimen.
METHODS...
BACKGROUND
The experience of children undergoing hematopoietic stem cell transplantation (HSCT), including the ways in which different participants (ie, children, parents, and nurses) contribute to the overall picture of a child's experience, is poorly characterized. This study evaluated parent, child, and nurse perspectives on the experience of children during HSCT and factors contributing to interrater...
BACKGROUND
Medical treatment for breast cancer is associated with substantial toxicity and patient burden. There is less known about the impact of surgical complications. Understanding this impact could provide important information for patients when they are considering surgical options.
METHODS
Between 2008 and 2009, the UK National Mastectomy and Breast Reconstruction Audit recorded surgical...
BACKGROUND
Cancer survivors transfused with blood products before reliable screening for hepatitis C virus (HCV) are at risk for infection. This study examined the impact of HCV on neurocognitive function and health‐related quality of life (HRQOL) among adult survivors of childhood cancer.
METHODS
Neurocognitive testing was conducted for 836 adult survivors of childhood cancer (mean age, 35 years...
BACKGROUND
The authors hypothesized that unilateral intensity‐modulated radiotherapy (IMRT) would decrease toxicity compared with bilateral IMRT for patients with lateralized palatine tonsillar cancer and a neck classification of N0 to N2b, with similar oncological outcomes.
METHODS
A total of 154 patients were treated with postoperative IMRT from 1997 through 2013. Data were collected prospectively...
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