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BACKGROUND
Given the rarity of anal cancer and the technical aspects involved in radiation (RT) planning, the authors conducted a population‐based analysis evaluating the impact of radiation oncology facility volume on overall survival (OS) in patients with squamous cell carcinoma (SCC) of the anal canal.
METHODS
The National Cancer Data Base (NCDB) was queried for patients with SCC of the anal...
BACKGROUND
Stage II and III rectal cancers have been effectively treated with neoadjuvant chemoradiotherapy (NCRT) followed by definitive resection. Advancements in surgical technique and systemic therapy have prompted investigation of neoadjuvant multiagent chemotherapy (NMAC) regimens with the elimination of radiation (RT). The objective of the current study was to investigate factors that predict...
BACKGROUND
The authors determined the impact of postmastectomy radiotherapy (PMRT) on overall survival (OS) among patients with pT3N0M0 breast cancer in the National Cancer Data Base.
METHODS
A total of 3437 patients with pT3N0M0 breast cancer who initially were treated with mastectomy between 2003 and 2011 were identified. Of these women, 1644 (47.8%) received PMRT (67% treated with chest wall...
BACKGROUND
Sinonasal malignancies are a rare and heterogeneous group of tumors for which there is a paucity of robust data with which to guide management decisions. The authors used the National Cancer Data Base to better understand the presenting characteristics of these tumors and to compare outcomes by treatment modality.
METHODS
The National Cancer Data Base was queried for sinonasal malignancies...
BACKGROUND
Extranodal natural killer T‐cell lymphoma, nasal‐type (NKTCL), is a rare malignancy in Western populations and is thus challenging for standardization of care and a prospective study. This study was aimed at defining patterns of care for NKTCL in the context of radiotherapy (RT) use and dose selection in the United States.
METHODS
Six hundred forty‐two stage I‐II NKTCL patients from...
BACKGROUND
The current study was conducted to compare the overall survival (OS) of concurrent chemoradiotherapy (CCRT) versus radiotherapy (RT) alone in elderly patients (those aged ≥80 years) with muscle‐invasive bladder cancer (MIBC).
METHODS
Patients aged ≥80 years with cT2‐4, N0‐3, M0 transitional cell MIBC who were treated with curative RT (60‐70 Gray) or CCRT were identified in the National...
BACKGROUND
The role of chemoradiotherapy (CRT) in locally advanced pancreatic cancer (LAPC) is uncertain after multiple randomized clinical trials have yielded mixed results. The authors used the National Cancer Data Base (NCDB) to determine whether CRT yields a survival benefit compared with chemotherapy alone (CT).
METHODS
Patients with nonmetastatic LAPC diagnosed during 2004 through 2014 were...
BACKGROUND
Risk stratification of patients with urothelial carcinoma of the bladder (UCB) after cystectomy has important clinical and research implications. The authors assessed the relative effect of tumor stage and lymph node status on cancer‐specific survival (CSS) after cystectomy and developed a simplified risk‐assessment tool.
METHODS
In total, 14,828 patients who underwent cystectomy with...
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