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BACKGROUND:Studying secondary hematological malignancies in a large cohort of patients can help predict risks and trends associated with current therapies.
METHODS:The authors analyzed data from the Surveillance, Epidemiology, and End Resultsecondary 9 (SEER‐9) database on patients with a primary malignancy (diagnosed before the age of 20 years) between 1973 and 2005 who developed a secondary hematological...
BACKGROUND:Female survivors of therapeutic chest radiation often question whether they will have difficulty with breast feeding, given their prior exposure to breast radiation. In the current study, the rates of successful breastfeeding in long‐term survivors who received chest radiotherapy (CXRT) as a treatment for Hodgkin lymphoma (HL) were examined.
METHODS:A survey study of survivors of HL who...
BACKGROUND:Navigation services may be strengthened by establishing a partnership between the patient, family/caregiver, and the navigator. Involvement of a patient's familial or social network in the navigation process would allow patient navigators to spend more time and resources with the subset of patients who do not have support from family and friends. The Partnership Approach evolves from combining...
BACKGROUND:The growing diversity of the population of the United States and the high burden of cancer‐related symptoms reflect the need for caregiver research within underserved groups. In this longitudinal study, the authors assessed changes in symptom severity in caregivers and underserved minority patients diagnosed with advanced solid tumors who were being treated at public hospitals.
METHODS:A...
BACKGROUND:The authors examined whether survivors from the Childhood Cancer Survivor Study were less likely to be in higher‐skill occupations than a sibling comparison and whether certain survivors were at higher risk for lower‐skill jobs.
METHODS:The authors created 3 mutually exclusive occupational categories for participants aged ≥25 years: Managerial/Professional, Nonphysical Service/Blue Collar,...
Cancer‐related fatigue (CRF) has been documented as 1 of the most distressing symptoms reported by breast cancer survivors. CRF affects functioning and impacts quality of life. Possible causal factors include physical conditions, affective and cognitive states, proinflammatory cytokines, and metabolic factors. Several common problems are associated with CRF in women with breast cancer, including treatment...
BACKGROUND:There is a need to better describe and understand the prevalence of breast cancer treatment‐related adverse effects amenable to physical therapy and rehabilitative exercise. Prior studies have been limited to single issues and lacked long‐term follow‐up. The Pulling Through Study provides data on prevalence of adverse effects in breast cancer survivors followed over 6 years.
METHODS:A...
BACKGROUND:The Female Sexual Function Index (FSFI) is the most commonly used self‐report instrument to measure sexual functioning among women cancer survivors. Despite this, the validity and reliability of the FSFI for use in cancer populations has not been established.
METHODS:Data were combined from 3 separate institutional review board‐approved studies of the psychosexual adjustment of women cancer...
BACKGROUND:Inflammation may underlie cancer‐related fatigue; however, there are no studies that assess the relation between fatigue and cytokines in patients with advanced disease versus patients without disease activity. Furthermore, the relation between cytokines and the separate dimensions of fatigue is unknown. Here, association of plasma levels of inflammatory markers with physical fatigue and...
This article presents the contrasting European and American perspectives on cancer‐related fatigue (CRF) and its impact on functioning in cancer survivors. The content is presented in 3 sections: state of the art, intervention studies, and future areas of research, followed by a discussion. Gaps identified include a lack of understanding of the etiology, definition, and measurement of CRF. Models...
BACKGROUND:Although rural residents are more likely to be diagnosed with more advanced cancers and to die of cancer, little is known about rural‐urban disparities in self‐reported health among survivors.
METHODS:The authors identified adults who had a self‐reported history of cancer from the National Health Interview Survey (2006‐2010). Rural‐urban residence was defined using US Census definitions...
BACKGROUND:Of the approximately 2.4 million American women with a history of breast cancer, 43% are aged ≥65 years and are at risk for developing subsequent malignancies.
METHODS:Women from 6 geographically diverse sites included 5‐year breast cancer survivors (N = 1361) who were diagnosed between 1990 and 1994 at age ≥65 years with stage I or II disease and a comparison group of women without breast...
BACKGROUND:More women of fertile age are long‐term survivors of cancer. However, population‐based data on birth rates of female cancer survivors are rare.
METHODS:A total of 42,691 women ≤ 45 years with a history of cancer were identified from the Swedish Multi‐Generation Register and the Swedish Cancer Register, for whom relative birth rates were calculated as compared to the background population,...
BACKGROUNDFinancial problems caused by cancer and its treatment can substantially affect survivors and their families and create barriers to seeking health care.
METHODSThe authors identified cancer survivors diagnosed as adults (n = 1556) from the nationally representative 2010 National Health Interview Survey. Using multivariable logistic regression analyses, the authors report sociodemographic,...
BACKGROUNDFew studies have examined the relationship of lifestyle factors with mortality among patients with colorectal cancer.
METHODSAmong NIH‐AARP Diet and Health study participants, 4213 colon and 1514 rectal cancer cases were identified through linkage to state cancer registries and determined date and cause of death using the National Death Index. Lifestyle factors were assessed at baseline...
BACKGROUNDFew studies to date have used the cancer diagnosis as a teachable moment to promote healthy behavior changes in survivors of cancer and their family members. Given the role of obesity in the primary and tertiary prevention of breast cancer, the authors explored the feasibility of a mother‐daughter weight loss intervention.
METHODSA randomized controlled trial of a mailed weight loss intervention...
BACKGROUNDAs cancer survivorship increases, health care systems will be challenged to meet patient needs. With the limited availability of clinician time and resources, novel methods of using patient‐reported outcomes may improve the quality and efficiency of follow‐up care in patients with breast cancer.
METHODSThe authors conducted a randomized trial in patients with TNM stage I to III breast cancer...
BACKGROUNDYoung adult female cancer survivors have unmet reproductive concerns and informational needs that are associated with poorer quality of life. The purpose of this study was to examine the association between current reproductive concerns and moderate to severe depression among young survivors.
METHODSThis cross‐sectional study included 200 female cancer survivors between the ages of 18 and...
BACKGROUNDCancer survivors' disclosure of complementary health approaches (CHAs) to their follow‐up care physicians is necessary to ensure the safe and optimal use of such approaches. Rates of disclosure of CHAs are variable and may be facilitated by patient‐centered communication.
METHODSThis cross‐sectional study conducted in 2003‐2004 examined a population‐based sample of leukemia, colorectal,...
BACKGROUNDLong‐term survivors of pediatric cancer are at risk of life‐threatening late effects of their cancer. Previous studies have shown excesses in long‐term mortality within high‐risk groups defined by demographic and treatment characteristics.
METHODSTo investigate conditional survival in a pediatric cancer population, the authors performed an analysis of conditional survival in the original...
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