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BACKGROUND:A large body of literature suggests that socioeconomic status (SES) is positively associated with mental and physical health. However, little research has examined the impact of SES on psychological adjustment after a major stressor. The current study examined whether SES (education and financial status) was associated with distress (anxiety and depression) in women diagnosed with ductal...
BACKGROUND:Multiple alterations in circadian rhythms have been observed in cancer patients, including the diurnal rhythm of the adrenal hormone cortisol. Diurnal cortisol alterations have been associated with cancer‐related physiological processes as well as psychological stress. Here we investigate alterations in diurnal cortisol rhythm in ovarian cancer patients, and potential links with depression,...
BACKGROUND:A few small studies published to date have suggested that major psychosocial problems develop in the partners of cancer patients; however, to the authors' knowledge, no studies to date have addressed their risk for severe depression. In a retrospective cohort study, the risk for hospitalization with an affective disorder of the male partners of women with breast cancer was investigated,...
BACKGROUND:Depression is highly prevalent in patients with pancreatic cancer and can result in fatal outcomes from suicides. The authors report suicide rates among patients with pancreatic cancer in the United States and identify factors associated with greater suicide rates.
METHODS:The current study reviewed data in the SEER database for patients diagnosed with pancreatic adenocarcinoma from 1995‐2005...
BACKGROUND:Up to 50% of prostate cancer (PC) patients receive androgen deprivation therapy (ADT), often for several years. Although depression has been reported after a diagnosis of PC, whether ADT leads to or worsens depression is not clear.
METHODS:Three groups were assembled: ADT users (men initiating continuous ADT), PC controls (PC patients who were not on ADT), and healthy controls. All 3 cohorts...
BACKGROUND:A key purpose of routine distress screening is to ensure that cancer patients receive appropriate mental health care. Most studies validating screening instruments overestimate the effectiveness of screening by not differentiating between patients with untreated disorders and patients who are already being treated. This study adopts the novel strategy of evaluating the effectiveness of...
BACKGROUND:There is considerable uncertainty regarding the acceptability of routine distress screening.
METHODS:In an unfunded implementation study, the authors asked 50 clinicians (chemotherapy nurses and treatment radiographers/radiation technologists) to implement a screening program for distress as part of routine care and to record their feedback after each clinical encounter. In total, 379...
BACKGROUNDDepression is common during and after breast cancer treatment. However, the role of specific therapeutic modalities and related biologic mechanisms remains unclear. Radiation is an essential component of breast‐conserving therapy and may contribute to depression in patients with breast cancer through the activation of inflammatory pathways.
METHODSDepressive symptoms and inflammatory mediators,...
BACKGROUNDSleep disturbance is a common clinical complaint of oncology patients and contributes to substantial morbidity. However, because most sleep studies have been cross‐sectional, associations between sleep quality and distress in patients with ovarian cancer over time remain unclear. This prospective longitudinal study examined rates of sleep disturbance; contributions of depression, anxiety,...
BACKGROUNDThe objective of the current study was to determine the best set of predictors of psychological disorders, regrets, health‐related quality of life, and mental health function among bereaved caregivers of patients with cancer, thereby identifying promising targets for interventions to improve bereavement adjustment.
METHODSCoping with Cancer is a longitudinal study of patients with advanced...
BACKGROUNDThe authors prospectively assessed anxiety, depression, and behavior in children with standard‐risk acute lymphoblastic leukemia (SR‐ALL) during the first year of therapy and identified associated risk factors.
METHODSA cohort study was performed of 159 children (aged 2 years‐9.99 years) with SR‐ALL who were enrolled on Children's Oncology Group protocol AALL0331 at 31 sites. Parents completed...
BACKGROUNDEpidemiological studies have shown prostate cancer (PC) survivors are at an increased risk of suicide compared with the general population, but to the authors' knowledge very little is known regarding what factors are associated with this increased risk. The current study examined the prevalence of suicidal ideation (SI) and its association with cancer treatment and posttreatment physical...
BACKGROUNDWe conducted a study to investigate the impact of hospitalization for hematopoietic stem cell transplantation (HCT) on the quality of life (QOL) and mood of patients and family caregivers (FC).
METHODSWe conducted a longitudinal study of patients who were hospitalized for HCT and their FC. We assessed QOL (using the Functional Assessment of Cancer Therapy‐Bone Marrow Transplantation) and...
BACKGROUNDYoung adult female cancer survivors have unmet reproductive concerns and informational needs that are associated with poorer quality of life. The purpose of this study was to examine the association between current reproductive concerns and moderate to severe depression among young survivors.
METHODSThis cross‐sectional study included 200 female cancer survivors between the ages of 18 and...
BACKGROUNDData on health‐related quality of life (HRQoL) changes among Americans aged ≥65 following colorectal cancer (CRC) diagnosis and treatment are limited. This study compared HRQoL changes among CRC patients across stages from before to after diagnosis with matched noncancer controls.
METHODSThis population‐based study used the Surveillance, Epidemiology, and End Results Medicare Health Outcomes...
BACKGROUND
Cancer not only affects patients but also their caregivers. The objective of the current study was to assess the unmet needs of cancer caregivers and to identify possible predictors of their supportive care needs.
METHODS
In a cross‐sectional survey, 188 dyads of patients diagnosed with lung, urological, or gastrointestinal cancer and their primary caregivers were recruited. Caregivers...
BACKGROUNDBreast cancer survivors experience long‐term physical and psychological sequelae after their primary treatment that negatively influence their quality of life (QOL) and increase depressive symptoms. Group‐based cognitive‐behavioral stress management (CBSM) delivered after surgery for early‐stage breast cancer was previously associated with better QOL over a 12‐month follow‐up and with fewer...
BACKGROUNDChildren whose parents have cancer are at risk for psychosocial difficulties; however, the mechanisms are not well understood. This cross‐sectional study sought support for a model connecting parental cancer to child distress through its impact on parenting self‐efficacy beliefs and parenting behaviors by examining relations among parental illness, quality of life/parent functioning, parenting...
Religion and spirituality (R/S) are patient‐centered factors and often are resources for managing the emotional sequelae of the cancer experience. Studies investigating the correlation between R/S (eg, beliefs, experiences, coping) and mental health (eg, depression, anxiety, well being) in cancer have used very heterogeneous measures and have produced correspondingly inconsistent results. A meaningful...
BACKGROUNDThe primary purpose of the current study was to determine prospective associations of accelerometer‐assessed physical activity intensity and sedentary time with health‐related quality of life (HRQOL) indicators among survivors of breast cancer.
METHODSA total of 358 survivors of breast cancer wore an accelerometer for 7 days at baseline to assess different activity intensities (light, lifestyle,...
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