This brief review describes a class of uniquely crafted particle physics experiments that typically each tackle just one investigation—and they do that very well. The aim of these experiments is to both establish Standard Model parameters and also to provide unique tests in search of new physics. I provide a brief snapshot of many of the current activities, selected with a bias toward low‐energy and high precision. These include searches for permanent electric dipole moments, charged lepton flavor violation, tests of the weak interaction, and other broad searches for deviations from very precise Standard Model predictions, such as the muon's anomalous magnetic moment. I highlight what drives these efforts and how they might impact a new Standard Model.