Numerical modeling of the generation and evolution of parental melts of the komatiite–tholeiite association of the Uraguba structure was carried out using previously obtained geochemical and isotope data. It was established that komatiite, komatiite and tholeiite basalts depleted in LREE and having εNd(Т = 2.79) = +2.9…+3.2 were generated by equilibrium partial melting (F > 15%) of a depleted source (garnet-bearing Ol0.63 + Opx0.22 + Cpx0.06 + Grt0.09 mantle peridotite) at 4–8 GPa, while the genesis of primary melts of LREE-enriched komatiites (LaN/SmN ~ 1.2–1.6) with εNd(Т = 2.79) = +2.5…+2.2 was related to the equilibrium partial melting (F > 20%) of an “enriched mantle peridotite” (EM–Ol0.60 + Opx0.20 + Cpx0.08 + Grt0.12) at pressure of 2.5–4 GPa. Coexistence in space and time of two types of melting products of mantle peridotites formed at different depths is explained by melting of different parts of adiabatically ascending mantle plume.