In this paper, MoS2/PbI2 heterostructures were synthesized via a two-step synthesis method using vapor deposition and direct water bath heating. Raman spectroscopy and Atomic Force Microscope were used to characterize the MoS2/PbI2 heterostructures. The Kelvin probe force microscope was characterized the surface potential of MoS2/PbI2 heterostructures. It has shown that the surface potential has undergone a significant change transfer in the interlayer between MoS2 and PbI2, which means that at the interface charge transfer occurs and the electrons transfer from MoS2 to PbI2. These results provide a theoretical basis for further understanding of the electrical properties of MoS2/PbI2 heterostructures.