Advances in cross-sectional imaging have led to an increasingly important role for radiology in the management of malignant gynecological conditions. A number of imaging modalities can be used to evaluate malignant diseases of the female pelvis, including ultrasound (US), computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography/computed tomography (PET/CT). These modalities have different roles in screening, diagnosis, staging, treatment selection and follow-up. The aim of this chapter is to review the role of different techniques in the imaging of malignant gynecological conditions. The emphasis is on the use of MRI in the staging of endometrial and cervical cancer following the revised FIGO (International Federation of Gynecology and Obstetrics) criteria, implemented beginning June 1, 2009 [1].