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Low-density lipoprotein (LDL)-cholesterol levels have been used as a surrogate marker and have been the focus of the management of coronary disorders for some time. In a 2-hour debate at the recent APOR*Lipid Conference [November 1997; Florida, US], worldwide experts discussed the role of LDL-cholesterol lowering and the relevance of other risk factors in the management of coronary heart disease (CHD). Dr Evan Stein, President of Medical Research Laboratories, Kentucky, US, argued that LDL-cholesterol reduction is the outcome of choice in CHD prevention, while Dr Jim Shepherd from the University of Glasgow, Scotland, argued that, in addition to LDL-cholesterol reduction, there are other outcomes that should be considered....
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