Leading the open access field for translational research into dementia and neurodegenerative diseases, Alzheimer's Research & Therapy is the major forum for translational research into Alzheimer's disease. Affiliated with Alzheimer’s Disease International (ADI), we publish basic research, as well as clinical trials, research into drug discovery and development, and epidemiologic studies. The journal offers rapid peer review with an average time to first decision within 5 weeks and publishes reviews, viewpoints, commentaries, debates and reports, as well as research articles.
Alzheimer's Research & Therapy
Description
Identifiers
e-ISSN | 1758-9193 |
Publisher
BioMed Central
Additional information
Data set: Springer
Articles
Alzheimer's Research & Therapy > 2019 > 11 > 1 > 1-13
Background Exercise is often proposed as a non-pharmacological intervention to delay cognitive decline in people with dementia, but evidence remains inconclusive. Previous studies suggest that combining physical exercise with cognitive stimulation may be more successful in this respect. Exergaming is a promising intervention in which physical exercise is combined with cognitively challenging tasks...
Alzheimer's Research & Therapy > 2019 > 11 > 1 > 1-11
Background The previously described and validated Erlangen Score (ES) algorithm enables interpretation of the cerebrospinal fluid (CSF) biomarkers of Alzheimer’s disease (AD), ordering them on an ordinal scale: from neurochemically normal (ES = 0) through improbable AD (ES = 1), possible AD (ES = 2 or 3), to probable AD (ES = 4). Here we assess the accuracy of the ES in predicting hazards of progression...
Alzheimer's Research & Therapy > 2019 > 11 > 1 > 1-11
Background Alcohol use has been identified as a risk factor for dementia and cognitive decline. However, some patterns of drinking have been associated with beneficial effects. Methods and Results To clarify the relationship between alcohol use and dementia, we conducted a scoping review based on a systematic search of systematic reviews published from January 2000 to October 2017 by using Medline,...