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Nd3+, La3+ and Ce3+ at proper concentrations had positive effects on the cell growth of Arnebia euchroma and production of shikonin derivatives. A mixture of rare earth elements (MRE, La2O3:CeO2:Pr6O11: Sm2O3 = 255:175:3:1, mol/mol) behaved the most remarkable effects. Two-stage culture was used for the cell proliferation and the biosynthesis of shikonin derivatives. After 20 days culture, 0.05 mM...
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