Biomedical Microdevices covers research in the diagnostic and therapeutic applications of Micro-Electro-Mechanical Systems, microfabrication, and nanotechnology. Topics include design, characterization, testing, modeling and clinical validation of microfabricated systems, and their integration on-chip and in larger functional units. The interests of the journal include systems for neural stimulation and recording; bioseparation technologies such as nanofilters and electrophoretic equipment; miniaturized analytic and DNA identification systems; biosensors; microtechnologies for cell and tissue research; tissue engineering; cell transplantation and the controlled release of drugs and therapeutic proteins. Coverage extends to biochemical modification and non-specific protein adsorption; fluid dynamics in micro- and nano-fabricated channels; electromechanical and structural response of microfabricated systems; interactions of microdevices with cells and tissues, including biocompatibility and biodegradation; and more.
Biomedical Microdevices
Description
Identifiers
ISSN | 1387-2176 |
e-ISSN | 1572-8781 |
DOI | 10.1007/10544.1572-8781 |
Publisher
Springer US
Additional information
Data set: Springer
Articles
Biomedical Microdevices > 2020 > 22 > 1 > 1-8
In this study, we propose a microchip that is sequentially capable of fluorescently staining and washing DNAs. The main advantage of this microchip is that it allows for one-step preparation of small amounts of solution without degrading microscopic bio-objects such as the DNAs, cells, and biomolecules to be stained. The microchip consists of two inlets, the main channel, staining zone, washing zone,...
Biomedical Microdevices > 2019 > 21 > 4 > 1-11
E-cadherin is a cell-cell adhesion protein that plays a prominent role in cancer invasion. Inactivation of E-cadherin in breast cancer can arise from gene promoter hypermethylation or genetic mutation. Depending on their E-cadherin status, breast cancer cells adopt different morphologies with distinct invasion modes. The tumor microenvironment (TME) can also affect the cell morphology and invasion...
Biomedical Microdevices > 2019 > 21 > 4 > 1-9
This study investigated the in vitro transdermal delivery of magnesium ascorbyl phosphate (MAP) through porcine ear skin treated with hyaluronic acid (HA) microneedles (MNs). In this study, the micro-molding method was used to fabricate HA MNs. HA solution (10% w/v) containing 3% of MAP was placed onto a poly(dimethyl siloxane) mold to fill the microchannels under vacuum followed by drying in a desiccator...