Acta Biotheoretica promotes theoretical biology, encompassing mathematical biology and the philosophy of biology, and paying special attention to the methodology of formation of biological theory. The journal welcomes papers on all kinds of biological theories. The range of coverage includes philosophy of biology, biomathematics, computational biology, genetics, ecology and morphology. Articles can present the process of theory formation in verbal or mathematical form. The journal sometimes presents purely methodological papers devoted to the historical origins of the philosophy underlying biological theories and concepts. Acta Biotheoretica also publishes critical book reviews, short commentaries on previous papers and short notes directing attention to interesting new theoretical ideas.
Acta Biotheoretica
Description
Identifiers
| ISSN | 0001-5342 |
| e-ISSN | 1572-8358 |
| DOI | 10.1007/10441.1572-8358 |
Publisher
Springer Netherlands
Additional information
Data set: Springer
Articles
article
Acta Biotheoretica > 2019 > 67 > 4 > 299-320
Models of gene regulatory networks (GRN) have proven useful for understanding many aspects of the highly complex behavior of biological control networks. Randomly generated non-Boolean networks were used in experimental simulations to generate data on dynamic phenotypes as a function of several genotypic parameters. We found that predictive relationships between some phenotypes and quantitative genotypic...
article
Acta Biotheoretica > 2019 > 67 > 4 > 321-359
Over the last few years, oncolytic virus therapy has been recognised as a promising approach in cancer treatment, due to the potential of these viruses to induce systemic anti-tumour immunity and selectively killing tumour cells. However, the effectiveness of these viruses depends significantly on their interactions with the host immune responses, both innate (e.g., macrophages, which accumulate in...
article
Acta Biotheoretica > 2019 > 67 > 4 > 273-297
Theoretical minimal RNA rings attempt to mimick life’s primitive RNAs. At most 25 22-nucleotide-long RNA rings code once for each biotic amino acid, a start and a stop codon and form a stem-loop hairpin, resembling consensus tRNAs. We calculated, for each RNA ring’s 22 potential splicing positions, similarities of predicted secondary structures with tRNA vs. rRNA secondary structures. Assuming rRNAs...
