Current Issues in Pharmacy and Medical Sciences

Items from 1 to 20 out of 30 results

article

Implant-supported prostheses versus conventional permanent and removable dentures

Agnieszka Koszuta, Jolanta Szymanska

Current Issues in Pharmacy and Medical Sciences > 2014 > 27 > 1 > 23-26

Social, economic and technological progress results in an increasing range of treatment and rehabilitation methods for patients with partial or complete edentulism. The role of the dentist is to inform the patient about the full range of available missing teeth treatment options leading to complete rehabilitation of the masticatory organ in agreement with the patient’s aesthetic and functional expectations...

article

Central sleep apnea – a case report

Andrzej Dybala, Monika Dyczko, Boguslaw Makaruk, Pawel Kicinski, more

Current Issues in Pharmacy and Medical Sciences > 2014 > 27 > 1 > 14-16

Central sleep apnea (CSA) is a disease characterized by repetitive episodes of the socalled central apneas during sleep. The disease has a very complex etiology. In clinical practice, the most important causes of CSA are disorders of the central nervous system, congestive heart failure or certain pathological changes of the respiratory muscles. We present a case of a 43-year-old male with severe...

article

Diagnostic problems with follicular thyroid cancer – case study

Monika Koziolek, Anna Sieradzka, Michal Jakuszewski, Lilianna Osowicz-Korolonek, more

Current Issues in Pharmacy and Medical Sciences > 2014 > 27 > 1 > 5-7

The diagnosis of follicular thyroid cancer is based on postoperative histopathology assessment. In its minimally invasive form, the signs of vascular invasion and capsular infiltration may sometimes be seen only in a small tumor fragment; hence, the diagnosis should be based on multiple histopathology specimens. This case study is a report on a 70-year-old female who was diagnosed with spinal metastasis...

article

Sources of patients’ knowledge on the treatment of missing teeth with implants

Jolanta Szymanska, Agnieszka Koszuta, Katarzyna Drop

Current Issues in Pharmacy and Medical Sciences > 2014 > 27 > 1 > 20-22

The number of patients who take the decision to have implantoprosthetic treatment keeps increasing. The aim of this study was to determine the sources of knowledge about possibilities of treating missing teeth with implants. The survey was conducted among 464 patients of both sexes aged from 20 to 74 years, treated with dental implants at the Non-Public Healthcare Centre “Dental” in Tomaszów Mazowiecki...

article

Review on analgesic effect of co-administrated ibuprofen and caffeine

Andrzej Polski, Regina Kasperek, Karolina Sobotka-Polska, Ewa Poleszak

Current Issues in Pharmacy and Medical Sciences > 2014 > 27 > 1 > 10-13

Pain is a symptom of many diseases and significantly affects the quality of life, so researchers are constantly seeking new substances to be used as analgesics. Other, easier way is to combine already known drugs which cause synergistic effects greater than additive, so that probability of drug-specific side effects can be reduced. Researchers showed that caffeine can be an effective analgesic adjuvant...

article

Plasma levels of catecholamines and asymmetric dimethylarginine levels as predictive values of mortality among hemodialysis patients

Marcin Dziedzic, Ewelina Orlowska, Kinga Gawel, Magdalena Zawadzka, more

Current Issues in Pharmacy and Medical Sciences > 2014 > 27 > 1 > 37-40

The aim of the study was to assess plasma concentration of catecholamines and asymmetric dimethyl arginine levels and a possible relationship to predict the mortality rates among hemodialysis patients. The study population comprised 27 subjects, aged 65-70 years. Each patient underwent dialysis thrice a week. Furthermore, the median duration of hemodialysis was 3.5 years. Based on the conducted research,...

article

FAPA mass spectrometry of hydroxychalcones. Comparative studies with classical methods of ionization

Marek Smoluch, Grazyna Bartkowiak, Edward Reszke, Wojciech Lechowicz, more

Current Issues in Pharmacy and Medical Sciences > 2014 > 27 > 1 > 27-31

In this paper we are focused on analysis of hydroxychalcones, i.e. 2’-hydroxychalcone, 3’-hydroxychalcone and 4’-hydroxychalcone, by the Flowing Atmospheric Pressure Afterglow mass spectrometry (FAPA-MS), and on comparison of the obtained data with other classical methods including ESI-MS, APCI, MALDI, and GC/EI-MS. The paper is presenting fragmentation pathways of both positive-, and negative hydroxychalcone...

article

Prevalence of hepatitis A virus antibodies in Central-Eastern Poland – a comparative study (1990-2012)

Dariusz Pachnia, Dorota Polz-Gruszka, Pawel Macielag, Malgorzata Polz-Dacewicz

Current Issues in Pharmacy and Medical Sciences > 2014 > 27 > 1 > 17-19

Hepatitis A virus (HAV) is an hepatotropic human picornavirus that is associated only with acute infection of liver. This pathogen is mainly transmitted through the faecal-oral route, by person-to-person contact, and also contaminated drinking water and food. This reserach presenting the comparative seroepidemiological study (1990/1999/2012) on HAV infection was carried out in population from south-eastern...

article

An analysis of potential costs of adverse events based on Drug Programs in Poland. Pulmonology focus

Monika Szkultecka-Debek, Mariola Drozd, Karina Jahnz-Rozyk, Nina Kiepurska, more

Current Issues in Pharmacy and Medical Sciences > 2014 > 27 > 1 > 32-36

The project was performed within the Polish Society for Pharmacoeconomics (PTFE). The objective was to estimate the potential costs of treatment of side effects, which theoretically may occur as a result of treatment of selected diseases. We analyzed the Drug Programs financed by National Health Fund in Poland in 2012 and for the first analysis we selected those Programs where the same medicinal...

article

Immunomodulatory and anti-inflammatory properties of macrolides

Magdalena Bulska, Daria Orszulak-Michalak

Current Issues in Pharmacy and Medical Sciences > 2014 > 27 > 1 > 61-64

Macrolides are a group of antibiotics whose activity is ascribable to the presence of the macrolide ring, to which one or more deoxy sugars may be attached. Two properties are inherent in this group of antibiotics, the immunomodulatory and the anti-inflammatory actions, ensuring great efficacy in a wide spectrum of infections. Macrolides demonstrate several immunomodulatory activities both in vitro...

article

Synthesis of new derivatives of 9-(2-pyridyl)-3-aryl(arylalkyl)- -2,4,5(9H)trioxo-7,8-dihydroimidazo[1,2-a][1,3,5]triazepine

Marzena Rzadkowska, Elzbieta Szacon, Maria Zun

Current Issues in Pharmacy and Medical Sciences > 2014 > 27 > 1 > 8-9

A series of new derivatives of 9-(2-pyridyl)-3-aryl(arylalkyl)-2,4,5(9H)trioxo-7,8- dihydroimidazo [1,2-a][1,3,5] triazepine was obtained by condensation of 1-[1-(2-pyridyl) imidazolidine-2-ylidene]-3-aryl(arylalkyl)ureas) with diethyl oxalic acid ester. Considering the structure of the obtained compounds, it can be expected that these compounds can reveal pharmacological activity.

article

In vitro evaluation of immunogenic properties of active dressings

Joanna Orlowska, Urszula Kurczewska, Katarzyna Derwinska, Wojciech Orlowski, more

Current Issues in Pharmacy and Medical Sciences > 2014 > 27 > 1 > 55-60

The aim of this study was in vitro evaluation of the level of the immune response in relation to wound dressings composed of alginate, calcium carboxymethylcellulose, and dibutyrylochitin and determination of the direction of response, which will make referring next to the results of in vivo phase possible. The subject of the experiments was to examine the commercially available, biodegradable...

article

Essential oil composition and variability of Hypericum perforatum L. from wild population in Kosovo

Avni Hajdari, Behxhet Mustafa, Dashnor Nebija, Albana Kashtanjeva, more

Current Issues in Pharmacy and Medical Sciences > 2014 > 27 > 1 > 51-54

Aerial parts of Hypericum perforatum L. (Hypericaceae) were collected from five wild populations in Kosovo, with aim to investigate the chemical composition and natural variation of essential oils between wild populations. This species could be considered of economic potential as it is widespread in Kosovo, on the other hand H. perforatum is one of the best-known medicinal herbs used in Kosovo folk...

article

Influence of the dissolution medium on the release of dehydroepiandrosterone from lipophilic suppositories

Regina Kasperek1, Krzysztof Galczynski, Magdalena Nalesniak, Karol Iwaniak, more

Current Issues in Pharmacy and Medical Sciences > 2014 > 27 > 1 > 46-50

Suppositories with cocoa butter containing dehydroepiandrosterone (DHEA) without and with the addition of Span 80 and Tween 80 as surfactants with low and high HLB values were prepared. The physical properties and the drug content of all prepared suppositories were in accordance with the pharmacopoeial requirements. The release study tests in three dissolution media such as water, lactic acid solution...

article

Cytotoxic activity of ethanolic extracts of Eleutherococcus species cultivated in Poland on HL60 leukemia cell line

Daniel Zaluski, Helena Danuta Smolarz, Anna Bogucka-Kocka

Current Issues in Pharmacy and Medical Sciences > 2014 > 27 > 1 > 41-45

The Eleutherococcus species including 40 species native to Asia are medicinal plants widely used in traditional medicine. Some of these species are cultivated at the botanical gardens in Europe. On the basis on our earlier studies it was concluded that the extracts of analyzed species act as antioxidants, inhibitors of MMPs, and cytotoxic against Jurkat 45 leukemia cell line. In this study, the anti-leukemic...

article

Zero crossing and ratio spectra derivative spectrophotometry for the dissolution tests of amlodipine and perindopril in their fixed dose formulations

Paulina Maczka, Anna Gumieniczek, Justyna Galeza, Rafal Pietras

Current Issues in Pharmacy and Medical Sciences > 2014 > 27 > 2 > 113-117

Dissolution tests of amlodipine and perindopril from their fixed dose formulations were performed in 900 mL of phosphate buffer of pH 5.5 at 37°C using the paddle apparatus. Then, two simple and rapid derivative spectrophotometric methods were used for the quantitative measurements of amlodipine and perindopril. The first method was zero crossing first derivative spectrophotometry in which measuring...

article

Utility of the chronic unpredictable mild stress model in research on new antidepressants

Karolina Pekala, Barbara Budzynska, Grazyna Biala

Current Issues in Pharmacy and Medical Sciences > 2014 > 27 > 2 > 97-101

Unpredictable chronic mild stress model was developed as an animal model of depression more than 20 years ago. Essential for this model is that after prolonged exposure of tested animals to a series of unpredictable mild stressors, a condition similar to anhedonia develops, which is observed in the majority of depressive disorders. Unpredictable chronic mild stress model is used nowadays in numerous...

article

A rare case of retained fourth molar teeth in maxilla and mandible. Case report

Mansur Rahnama, Anna Szyszkowska, Marta Pulawska, Joanna Szczerba-Gwozdz

Current Issues in Pharmacy and Medical Sciences > 2014 > 27 > 2 > 118-120

The study presents a case of the rarely occurring totally retained fourth molar teeth simultaneously in maxilla and mandible. The appearance of supernumerary teeth is a relatively uncommon dental anomaly and it is rare for patients to have impacted fourth molars in two quadrant. The aim of this work is to describe the presence of unilateral (right) fourth molars in the maxilla and the mandible in...

article

Different faces of a febrile state

Ewa Rymarz, Sylwia Milaniuk, Andrzej Prystupa, Jerzy Mosiewicz

Current Issues in Pharmacy and Medical Sciences > 2014 > 27 > 2 > 111-112

Fever develops in various diseases. It is mainly associated with infectious diseases but can also occur in non-infectious ailments. Clinical symptoms are not always explicit, which can hinder the diagnosis and delay the institution of appropriate treatment. The aim of the study is to present difficulties in diagnosing the cause of a febrile state in a patient with splenic abscess.

article

Effect of N-(m-bromoanilinomethyl)-p-isopropoxyphenylsuccinimide on the anticonvulsant action of four classical antiepileptic drugs in the mouse maximal electroshock-induced seizure model

Jarogniew J. Luszczki, Ewa Marzeda, Maria W. Kondrat-Wrobel, Daniel Pyrka, more

Current Issues in Pharmacy and Medical Sciences > 2014 > 27 > 2 > 76-79

The purpose of this study was to determine the effects of N-(m-bromoanilinomethyl)- p-isopropoxyphenylsuccinimide (BAM-IPPS - a new succinimide derivative) on the protective action of four classical antiepileptic drugs (AEDs: carbamazepine [CBZ], phenobarbital [PB], phenytoin [PHT] and valproate [VPA]) in the mouse maximal electroshock (MES)-induced tonic seizure model. Tonic hind limb extension (seizure...

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2014 (30)

Keywords

DEMOGRAPHIC FACTORS (2)
INFLAMMATION (2)
PHENOLIC ACIDS (2)
1-[1-(2-PYRIDYL)IMIDAZOLIDINE- 2-YLIDENE]-3-ARYL(ARYLALKYL) UREAS) (1)
ACCESS OF INFORMATION (1)
ADVERSE DRUG EVENTS (1)
AILANTHUS GLANDULOSA DESF. (1)
ALKALINE PHOSPHATASE (1)
AMLODIPINE AND PERINDOPRIL (1)
ANALGESIC (1)
ANHEDONIA (1)
ANTI-HAV (1)
ANTIBIOTICS (1)
ANTIDEPRESSANTS (1)
ANTIEPILEPTIC DRUGS (1)
APOPTOSIS (1)
ASYMMETRIC DIMETHYLARGININE (1)
BIOFILM (1)
BIPAP ST (1)
BNP (1)
BONE METASTASIS (1)
BONE TURNOVER MARKERS (1)
BREAD (1)
CAFFEIC ACID (1)
CAFFEINE (1)
CARIES DETECTION (1)
CATECHOLAMINES (1)
CHROMIUM (1)
CIMICIFUGA RACEMOSA (1)
COLLAGENASES (1)
CYTOTOXICITY (1)
DEHYDROEPIANDROSTERONE (1)
DENTAL ANOMALIES (1)
DENTAL IMPLANTS (1)
DEPRESSION (1)
DERIVATIVE SPECTROPHOTOMETRY (1)
DERIVATIVES (1)
DIETHYL OXALIC ACID ESTER (1)
DISSOLUTION (1)
DISSOLUTION MEDIUM (1)
DOXORUBICIN (1)
DRESSINGS (1)
E. COLI ATCC 25922 (1)
ELEUTHEROCOCCUS (1)
ELEUTHEROSIDES (1)
ENTRAL SLEEP APNEA (1)
ESSENTIAL OIL (1)
FAPA (1)
FEBRILE STATE (1)
FIXED DOSE FORMULATIONS (1)
FOURTH MOLAR (1)
GELATINASES (1)
H-FABP (1)
HAV (1)
HEALTH CARE COSTS (1)
HEART FAILURE (1)
HEMODIALYSIS (1)
HL60 (1)
HYDROXYCHALCONES (1)
HYPERICUM PERFORATUM (1)
IBUPROFEN (1)
ICDAS (1)
IMMUNE RESPONSE (1)
IMMUNOMODULATION (1)
IMPACTED TOOTH (1)
IMPEDANCE SPECTROSCOPY (1)
IMPLANT PROSTHETIC TREATMENT (1)
INHIBITOR (1)
IRON (1)
KOSOVO (1)
LASER FLUORESCENCE (1)
MACRODONTIC TOOTH (1)
MACROLIDES (1)
MANDIBULAR FRACTURES (1)
MANGANESE (1)
MASS SPECTROMETRY (1)
MAXIMAL ELECTROSHOCK-INDUCED SEIZURES (1)
MENOPAUSAL PERIOD (1)
MICE. (1)
MINIMALLY INVASIVE FOLLICULAR (1)
MMP-1 (1)
MMP-13 (1)
MMP-2 (1)
MMP-8 (1)
MMP-9 (1)
N-(M-BROMOANILINO-METHYL)-P-ISOPROPOXYPHENYLSUCCINIMIDE (1)
NATURAL VARIABILITY (1)
NICKEL (1)
ORAL SURGERY (1)
ORTHODONTIC TREATMENT (1)
OVARECTOMY HORMONE REPLACEMENT THERAPY (1)
PHOSPHOGLUCOSE ISOMERASE (1)
PROSTHETIC REPLACEMENTS (1)
PROTEASOM (1)
PULMONARY MEDICINE (1)
RELEASE (1)
RENAL FAILURE (1)
RODENTS (1)
SEROPREVALENCE (1)
SERVO-VENTILATION (1)
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INFONA - science communication portal

Current Issues in Pharmacy and Medical Sciences

Implant-supported prostheses versus conventional permanent and removable dentures

Central sleep apnea – a case report

Diagnostic problems with follicular thyroid cancer – case study

Sources of patients’ knowledge on the treatment of missing teeth with implants

Review on analgesic effect of co-administrated ibuprofen and caffeine

Plasma levels of catecholamines and asymmetric dimethylarginine levels as predictive values of mortality among hemodialysis patients

FAPA mass spectrometry of hydroxychalcones. Comparative studies with classical methods of ionization

Prevalence of hepatitis A virus antibodies in Central-Eastern Poland – a comparative study (1990-2012)

An analysis of potential costs of adverse events based on Drug Programs in Poland. Pulmonology focus

Immunomodulatory and anti-inflammatory properties of macrolides

Synthesis of new derivatives of 9-(2-pyridyl)-3-aryl(arylalkyl)- -2,4,5(9H)trioxo-7,8-dihydroimidazo[1,2-a][1,3,5]triazepine

In vitro evaluation of immunogenic properties of active dressings

Essential oil composition and variability of Hypericum perforatum L. from wild population in Kosovo

Influence of the dissolution medium on the release of dehydroepiandrosterone from lipophilic suppositories

Cytotoxic activity of ethanolic extracts of Eleutherococcus species cultivated in Poland on HL60 leukemia cell line

Zero crossing and ratio spectra derivative spectrophotometry for the dissolution tests of amlodipine and perindopril in their fixed dose formulations

Utility of the chronic unpredictable mild stress model in research on new antidepressants

A rare case of retained fourth molar teeth in maxilla and mandible. Case report

Different faces of a febrile state

Effect of N-(m-bromoanilinomethyl)-p-isopropoxyphenylsuccinimide on the anticonvulsant action of four classical antiepileptic drugs in the mouse maximal electroshock-induced seizure model

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