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Shape design optimization for an untethered microdevice meant to navigate in the human bloodstream is studied based on previous variational finite element (FE) work done. The suggested shape for a first generation prototype is a prolate spheroid design, which enables to minimize the drag force and to maximize the use of the MRI's magnetic gradients
The greatest merit of magnetic resonance (MR) methodology applied to medicine is its capabilities of measuring a variety of physiological parameters in vivo. MR imaging (MRI) with unique imaging contrasts can provide vital information which tightly links to brain functions at both normal and diseased states. In contrast, in vivo MR spectroscopy (MRS) is capable of determining metabolites, bioenergetics...
This paper presents potential medical applications that an untethered microdevice in the cardiovascular system could perform within an MRI system. Recent developments and continuing evolution in micro/nano fabrication and design techniques will enable the development of functional microdevices able to explore the cardiovascular system. The magnetic resonance submarine (MR-Sub) project is a first step...
A new method for the propulsion of a spherical ferromagnetic device along a given path in a water filled phantom with no human interaction is presented using an 1.5 T magnetic resonance imaging (MRI) clinical system. A special real time loop is implemented and presented that feeds the scanner with the appropriate gradients amplitudes and directions based on a pre-determined path. This paper studies...
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