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The authors describe a 3-D computer animation of kinematic data with superimposed center of gravity and force vectors on a wire-like figure. This animation is used to provide ease in visualizing kinematic and kinetic data obtained by the motion analysis system at the Biomotion Laboratory at Massachusetts General Hospital. The animation permits qualitative assessment of data validity. In conjunction...
A system was developed to simulate the operation of an intra-aortic balloon pump (IABP) console, and the corresponding patient response. It displays aortic pressure and left ventricular pressure as sliding waveforms in real-time, as well as all of the IABP controls. The system is designed to execute in a PC architecture. The embedded arterial model is based on a multiple-order nonlinear system model...
The authors examined the dynamics of an intra aortic balloon (IAB) in the aorta and its effect on the hemodynamic response of the cardiovascular system. A mathematical model was developed and in vivo animal experiments were performed. The model describes the balloon inflation and deflation as an aortic-pressure-dependent wavefront. To validate the model, X-ray images and hemodynamic waveforms were...
Summary form only given. An attempt has been made to construct a mathematical model of the cardiovascular system which will allow one to simulate the effects of changes in one or more hemodynamic parameters on myocardial oxygen supply and demand. The model used is a combination of several models which have been reported in the literature, along with the authors' own modifications.<<ETX>>
Summary form only given. The authors review the properties and functional characteristics of the H/sub 1/ receptor and postulate the nature of the ligand-receptor activation site using molecular modeling techniques. A model of the surface of the active site on the receptor was postulated and constructed using Sybyl software on a personal Iris workstation. The surface properties were inferred using...
Summary form only given. Burn wounds are imaged with an infrared charge-coupled device camera. The camera is composed of an 320*244 array of platinum silicide Schottky-barrier infrared detectors, operating at liquid nitrogen temperature. The system operates in the medium wavelength infrared range of 3-5 mu m. With careful calibration and adjustments, a black-and-white image composed of 256 gray levels...
An investigation is being pursued to determine the best pH sensor for assessing tissue viability during the process of reconstructive surgery. Two different pH sensors are being evaluated in a preliminary study designed to improve upon the standard glass pH electrode: an ion-selective field effect transistor (ISFET) sensor and a conventional glass electrode. Preliminary test results show that the...
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