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Stretch-activated ion channels (SACs) in myocytes isolated from neonatal rats were studied in cell-attached patches. Stretch was applied to cell-attached patches by suction (5-20 mm Hg) in the recording pipet. Stretch caused the triggering of action potentials that were recorded in cell-attached patches as biphasic action currents (ACs). The significance of a temporal correlation between SAC open...
A novel thresholding method to separate the myocardium of correct thickness from a sequence of two-dimensional echocardiograms is presented. The threshold is made adaptive by maintaining a constant wall width ratio throughout the image sequence. The width ratio is computed at an interactively indicated wall section where the wall width is known a priori. The method is well suited for detecting the...
A procedure has been developed to determine the number of pulses and interpulse intervals necessary for an N-let (set of N closely spaced stimulation pulses) to elicit the maximal twitch response in human skeletal muscle. It was found that using a doublet (N=2) produced the largest force-time integral per pulse. Since muscular fatigue during electrical stimulation is believed to be a function of the...
The characteristics of physical manual dexterity are defined and analyzed to provide the basis for a numerical rating system. Physical manual dexterity is based on the actual functionality and fitness of the hand and is assessed independently of higher neural ability. A method has been developed to test and analyze define characteristics. This method is expanded and integrated into a quantitative...
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