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A 16-channel implantable microelectrode array (MEA) was designed and fabricated by Micro-electromechanical Systems (MEMS) technology. Then the electrode sites were modified with platinum/graphene oxide nanocomposites (Pt-GO) by one-step electrochemical deposition and later handled by cyclic voltammetry reduction in phosphate buffer solution. Finally, a Nafion thin film was coated on the MEA surface...
Regenerative peripheral-nerve interfaces are a novel method for integrating with the peripheral nervous system. These devices have the potential to isolate and transduce both afferent (sensory) and efferent (motor) neural signals to produce fine control of advanced prosthetics. We have developed a novel regenerative device comprised of microfabricated polyimide electrode threads supported by a hydrogel...
How the brain maintains the stability of visual perception across saccade is a central question in systems neuroscience; accurately characterizing visual responses in the perisaccadic period is an important step towards understanding how the visual world is represented during saccades. Here, we develop a probabilistic model in the Generalized Linear Model framework to characterize and predict the...
A significant and recognized problem in implantable neural recording and stimulation probes is operational lifetime. It is well known that both electrophysiological recording and, to a lesser extent, stimulation probes suffer severe performance degradation over periods ranging from months to a few years. Performance degradation of implantable probes arises due to a number of factors, including systemic...
Silicon neural probes with sophisticated integrated CMOS-based electronics providing a large number of recording sites integrated along the slender probe shanks have become a driving force in neural engineering throughout the past decade. Using such neural probes in a chronic setting often requires to mechanically anchor them with respect to the skull. Any relative motion between brain and implant...
Microfabrication technology can enable extracellular neural recording electrodes with unprecedented wiring density, and the ability to benefit from continued CMOS technology scaling. A neural recording electrode consists of recording sites that sense electrical activity inside the brain, and wiring that routes these signals to neural amplifiers outside the brain. We here introduce a scalable circuit...
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