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Maintaining the insulation between adjacent electrical interconnections is critical for the success of active implantable medical device. Underfilling and globtop coating of dense arrays of microfabricated interconnects pose a big reliability risk. Contamination, voids and the difficulty to deposit liquid underfillers with the appropriate adhesive behavior remains a major hurdle when developing miniaturized...
In this study, we describe a novel peripheral-nerve interface which makes use of highly flexible multi-electrode arrays that are integrated into hydrogel-based scaffolds to form a hybrid tissue-engineered electronic construct. This tissue-engineered electronic nerve interface (TEENI) is designed to be scalable to high channel counts using multiple polyimide-based “threads” that are evenly distributed...
A significant and recognized problem in implantable neural recording and stimulation probes is operational lifetime. It is well known that both electrophysiological recording and, to a lesser extent, stimulation probes suffer severe performance degradation over periods ranging from months to a few years. Performance degradation of implantable probes arises due to a number of factors, including systemic...
Neural-interface devices have the potential to isolate and transduce both afferent (sensory) and efferent (motor) neural signals of the peripheral nerve to and from electrical signals in instrumentation for stimulation and recording to produce fine control of advanced prosthetics. In order to potentiate the full spectrum of possible applications, the persistent foreign-body response needs to be addressed...
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