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Parkinson's disease (PD) is a progressive, neurodegenerative disorder, characterized by hallmark motor symptoms. Deep brain stimulation (DBS) has been used to treat advanced PD successfully. Previous studies have found that the DBS also has an effect on the electrophysiological activity of the deep brain nucleus while alleviate the PD symptoms. Here, in an attempt to gain a greater understanding of...
Deep brain stimulation (DBS) is a common therapy for the treatment of essential tremor (ET). Currently, this technology continuously delivers stimulation to deep brain regions to mitigate symptoms. Closed-loop DBS aims to deliver stimulation only when symptoms are present, thus improving battery life and decreasing potential side effects. In this study, we used an investigational DBS device implanted...
Animal studies are often used to test the feasibility and effectiveness of neuroscience research ideas. Optogenetics is a state-of-the-art technique that allows researchers to control brain activity with light. Current methods are limited as they use tethered setups with the animal in a fixed position, resulting in stress and reduced animal welfare. Hence, an untethered setup is highly desirable.
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