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Demonstrating the mechanisms of cardiac spiral waves is crucial in developing methods for heart arrhythmia elimination. This study constructed a two dimensional single layer heart tissue based on the Luo-Rudy model to investigate why spiral wave would rotate around the center and how energy efficiency would change across the tissue. The results demonstrated that a functional block area existed inside...
Spike-frequency adaptation is one of the most prominent features in the neural system, which is of importance in neural electrical information processing. Manual acupuncture is an ancient sophisticated therapeutic method. Manipulation to the acupoint is a kind of mechanical stimulation to the neural system. In this paper, an acupuncture experimental design is proposed, that is, different manipulations...
This paper means to explore the application of input-output feedback linearization method to control the model-based firing behavior. The Pinsky-Rinzel (PR) model is used to develop the feedback controller. The epileptiform behavior is modeled by the high frequency burst of 29 Hz and the normal desired behavior is modeled by the periodic firing of 6 Hz. The epilepsy treatment is formulated as a classic...
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