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We have demonstrated multi-walled carbon nanotube (MWCNTs) based sensors, which are capable of detecting alcohol vapor with ultra-low power. We fabricated the Si-substrate sensors using an AC electrophoretic technique so as to form bundled MWCNTs sensing elements between Au microelectrodes. The I-V measurement illustrates that we can activate the sensors at the Ohmic region of the sensors (at 10 muA),...
Silicon nanostructures were fabricated by a natural lithography technique, with sizes far beyond the limit of conventional, by a self-organizing gold colloidal particle monolayer as an etch mask. The silicon nanostructures with high density and uniformity in height and shape were obtained using reactive ion etching (RIE). The uniform spatial distribution of the Si nanostructures can also be obtained...
The paper describes an approach for preparing probes for combined SPM techniques, such as scanning electrochemical microscopy (SECM)/photoelectrochemical microscopy (PEM), SECM/near-field scanning optical microscopy (NSOM). The SECM/PEM probes were constructed firstly by stripping off a single mode optical fiber's polymer coating (125 mum diameter of cladding) at one end. The stripped optical fibers...
Three SPM-based techniques are put forward to fabricate 1D and 2D nanoscale reference materials, i.e. atomic force microscopy (AFM) tip-induced anodic oxidation on Si substrate, scanning tunneling microscopy (STM) current-induced oxidation on Ti film as well as AFM tip-scratching on Au film. The experimental parameters are analyzed and classified. For AFM tip-induced anodic oxidation on Si substrate...
This paper presents a CMOS biochip for DNA detection with an embedded current amplifier circuit by using self-assembly multilayer gold nanoparticles (AuNPs). The biochip is fabricated by a TSMC 0.35 mum 2P4M standard CMOS process and post-CMOS micromachining processes. On each measuring spot, there is a pair of electrodes with a gap distance of 350 nm. Through a self-assembly process between suspended...
Gold-coated microcantilevers were used to develop sensitive micromechanical biosensor for detecting mismatch mutations in DNA hybrids. The selective 5'-end immobilization of 25-mer single-stranded (ss) DNA probes to a gold-coated cantilever surface and the specific hybridization of ssDNA targets to the immobilized probe were performed by the direct electric field control. The controlled electric fields...
A new localized surface plasmon resonance sensor fabricated by the nanoimprinting technique is presented. Nanoimprinting, one of the most important nanofabrication technologies, can produce stable nanopatterns on a substrate with high throughput. In this study, we apply this technique to the preparation of sensor chips for a low-cost and reliable biosensor. The optimal cross-sectional structure of...
The phonon spectra in 7-1 structure of gold nanowire, which is the simplest structure among possible helical multi-shell nanowire, are studied by using molecular dynamics simulations with a tight-binding many-body potential. Our simulation identifies the outer tube (shell) and inner gold-atom row (core strand) vibrational modes. Generally, atomic interactions have a stiffening force constant due to...
A disposable biosensor for the determination of hemoglobin in whole blood is described. The sensing method is based on amperometric detection technology. Platinized thin-film gold electrode is employed as a base electrode for the immobilization of mediator potassium ferricyanide. Saponin hemolyses the erythrocytes and hemoglobin is released. The biosensor has characters of rapid response time (60...
A novel amperometric immunosensor fabricated by microelectromechanical systems (MEMS) technology with a novel modified procedure for immobilization of antibody on gold electrode has been developed. Based on MEMS technology, immunosensor with a three-microelectrode system integrated with two SU-8 micro pools was fabricated. Employing self-assembled monolayers technique, the working electrode was modified...
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