Innovation is the distinctive theme of our times and innovation spirit is the greatest Zeitgeist. Innovation is the best generalization on human society but also the exemplification of Zeitgeist and soul. Competition in current is the competition of talent and science & technology strength, and innovation is the essence of science & technology. That can be found by looking back the history of society development times focus has shifted to cultural development from politics and economy, at the same time, science & technology innovation has a rich cultural heritage. The culture in science & technology innovation is an important part of the whole social cultural system, and is the collective result of participating in science & technology innovation activities, and its evolution originates actions from science & technology innovation subjects. Based on culture, science & technology innovation regulates the innovators' behaviors and provides the most lasting and stable strong power for social economic development.