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We demonstrate for the first time a depletion mode field effect transistor fabricated on GaAs which is grown on top of a lattice-mismatched InP substrate by molecular beam epitaxy. This structure looks promising for the monolithic integration of metal-semiconductor field effect transistors (MESFETs) with photoconductive detectors and other optoelectronic devices. We observe an orientation-dependent surface conductance property. Preliminary experiments reveal a transconductance of about 20 mS/mm.