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The myotoxic Lys-49 phospholipase bothropstoxin I was crystallized, and X-ray diffraction data were collected to 3.5 Å resolution. Preliminary analysis reveals the presence of four molecules in the asymmetric unit.
The physiological effects of domoic acid on the immune system of marine invertebrates, which are known to accumulate this neurotoxin, have not been investigated previously. Changes in the number and relative phagocytic activity of circulating haemocytes in Crassostrea gigas exposed to domoic acid in the diatom Pseudonitzschia pungens f. multiseries for 48 hr, followed by clearance for 240 hr, were...
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