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Early life environmental exposure to pesticides could play a critical role in the onset of age-related diseases.The present study aims to evaluate in brain, plasma and leukocytes of 300day-old rats, the effect of a low dose of the insecticide permethrin administered during early life (1/50 LD 50 , from 6th to 21st day of life).The outcomes show that Nurr1, mRNA and protein expression, as well...
The diagnosis of vascular dementia (VaD) describes a group of various vessel disorders with different types of vascular lesions that finally contribute to the development of dementia. Most common forms of VaD in the elderly brain are subcortical vascular encephalopathy, strategic infarct dementia, and the multi infarct encephalopathy. Hereditary forms of VaD are rare. Most common is the cerebral autosomal...
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