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The influence of surface structuring on surface acoustic wave (SAW) biosensor signals has been investigated. Polymer structures on the sensor surfaces were applied by lithography or by self-assembling of polystyrene microparticles. In first experiments, structured and unstructured sensors led to similar results in a model affinity assay using streptavidin and biotinylated protein. On the other hand,...
Polymers are common housing materials in biosensor chips, but are often chemically less resistant than the biosensor components. Hence, modification procedures optimized for biosensor surfaces may affect potential chip materials. Still, it might be more economic to re-adapt a surface modification procedure than to re-establish a chip fabrication process with a chemically more stable polymer. In the...
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