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A contact lens (CL) biosensor for in situ monitoring of tear glucose was fabricated and tested. Biocompatible 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer and polydimethyl siloxane (PDMS) were employed as the biosensor material. The biosensor consists of a flexible Pt working electrode and a Ag/AgCl reference/counter electrode, which were formed by micro-electro-mechanical systems (MEMS)...
Metal oxide nanoparticles prepared by pulsed laser deposition (PLD) were applied to nonenzymatic glucose detection. NiO nanoparticles with size of 3nm were deposited on glassy carbon (GC) and silicon substrates at room temperature in an oxygen atmosphere. Transmission electron microscope (TEM) image showed nanoparticles with the size of 3nm uniformly scattered on the Si(001) substrate. Unlike co-sputtering...
A novel saccharide sensor that shows a distinct color change resembling a “traffic signal” was developed. By copolymerizing a boronic acid monomer and an amine monomer on a glass plate, a boronic acid-containing thin film was obtained. After adsorbing anionic blue and yellow dyes, the thin film was immersed in aqueous saccharide solutions containing a cationic red dye. As saccharide concentration...
In this paper, we utilized the instinct peroxidase-like property of Fe 3 O 4 magnetic nanoparticles (MNPs) to establish a new fluorometric method for determination of hydrogen peroxide and glucose. In the presence of Fe 3 O 4 MNPs as peroxidase mimetic catalyst, H 2 O 2 was decomposed into radical that could quench the fluorescence of CdTe QDs more efficiently...
Gold nanoparticles (GNPs) embedded in a Bucky gel consisting of carbon nanotubes (CNTs) and ionic liquid (IL) show an excellent electrocatalytic activity to glucose oxidation owing to some synergistic effects among GNPs, CNTs and IL. Each component in such a composite has its specific function while there are complicate interactions among them. Based on this strategy, the use of composite as the modified...
In this paper, an enzyme-free amperometric electrochemical sensor was fabricated by casting Nafion-impregnated Cu 2 O particles onto a glassy carbon electrode. A dual dependence of peak current on sweeping rate, which can be attributed for the accumulation of reaction products, was observed on the sensor. Electrochemical analysis of the particulate Cu 2 O for detecting H 2 ...
Microdialysis is an extensively used technique for both in vivo and in vitro experiments, applicable to animal and human studies. In neurosciences, the in vivo microdialysis is usually performed to follow changes in the extracellular levels of substances and to monitor neurotransmitters release in the brain of freely moving animals. Catecholamines, such as dopamine and their related compounds, are...
Paper-based microfluidic devices are an alternative technology for fabricating simple, low-cost, portable and disposable platforms for clinical diagnosis. Hereby, a novel wax dipping method for fabricating paper-based microfluidic devices (μPADs) is reported. The iron mould for wax dipping was created by a laser cutting technique. The designed pattern was transferred onto paper by dipping an assembly...
In this report, we presented a new method to fabricate TiO 2 nanotube (TiO 2 NT) arrays modified with cupric oxide (CuO) nanofibers, getting a novel TiO 2 NT arrays composition electrode for sensitive nonenzymatic glucose detection. For the preparation of CuO nanofibers, Cu nanoparticles were firstly electrodeposited onto the TiO 2 NT arrays, and then oxidized to CuO...
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