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Based on Co-Co Prussian blue analogue (Co-Co PBA), a novel immunosensor has been developed for sensitive detection of prion protein (PrPC). Gold nanoparticles (AuNPs)-modified Co-Co PBA nanocubes (PBA-AuNPs) worked as a support of the antibody (Ab2) of PrPC to obtain Ab2-PBA-AuNPs composite and also as the signal source for PrPC assay. When PrPC existed, Ab2-PBA-AuNPs could be introduced to the surface...
This work proposed an electrochemiluminescence (ECL) immunosensor for quantitative monitoring of cardiac troponin I (cTnI) in plasma with soybean peroxidase (SBP) labeled-antibody as signal amplifier. The ECL sandwich immunosensor was constructed by covalent binding anti-cTnI capture antibody (Ab1) to polyethylenimine-functionalized graphene matrix, which was obtained by a simple hydrothermal reaction...
In this paper we propose an easy way to detect the glycated form of human serum albumin which is biomarker for several diseases such as diabetes and Alzheimer. The detection platform is a label free impedimetric immunosensor, in which we used a monoclonal human serum albumin antibody as a bioreceptor and electrochemical impedance as a transducing method. The antibody was deposited onto a gold surface...
The accurate and rapid ochratoxin A (OTA) detection at early stage can prevent people from getting cancer to a great extent due to its strong liver toxicity and renal toxicity. The development of an efficient strategy to detect OTA without sophisticated instruments is highly desired, but still remains a severe challenge. In this communication, a sandwich type point-of-care testing (POCT) immunoassay...
We present a paper-based microfluidic colorimetric immunosensor for the detection of carcinoembryonic antigen (CEA), using Co2(OH)2CO3-CeO2 nanocomposite with extraordinary intrinsic peroxidase like activity. The morphology and composition of the nanocomposite characterized with Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), X-ray diffraction (XRD) and X-ray photoelectron...
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