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Nicotine (NIC), the major active component of tobacco, is critical in the maintenance of the smoking habit. The aims of the present study were to analyze the behavioural and neurochemical variations during NIC withdrawal syndrome in mice, and whether they are prevented with baclofen (BAC, GABA B receptor agonist).Swiss-Webster albino mice received NIC (2.5mg/kg, s.c.) 4 times daily, for 7...
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