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Polymer-based drug delivery systems are attracting interest for biomedical and, in particular, oncology-related applications due to interesting characteristics in terms of prolonged drug release. In this study, we investigated a new poly(lactic acid) (PLA)-based drug delivery system in which the cationic chemotherapeutic drug doxorubicin was adsorbed via ionic interactions. PLA, a polyester already...
Laccase from ascomycete Myceliophthora thermophila was used for the oxidation and grafting of catechin (CA) and chitosan (CS). The enzymatic grafting of CA into CS resulted in the improvement of natural properties of chitosan films. The successful grafting of CA to CS was supported by UV–vis and Fourier transform infrared (FT-IR) spectroscopies. The differences in the molecular weight and the degree...
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