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The usefulness of several statistical designs in experimental optimisation including Box-Behnken, Central Composite Rotatable and Plackett-Burman designs in lipase catalysed esterification reactions is presented. Analyses of several response surface plots obtained by employing statistical designs in lipase catalysed esterification reactions have indicated that such plots could be grouped into four...
Statistical optimization of culture conditions for production of a widely suited detergent protease from Bacillus sp. RGR-14 was carried out using a two-step approach. A quick identification of the important factors with simple screening experiment was followed by application of complex response surface design for further optimization. The production of extracellular alkaline protease by Bacillus...
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