In this paper, heat and mass transfer analysis for boundary layer stagnation-point flow over a stretching sheet in a porous medium saturated by a nanofluid with internal heat generation/absorption and suction/blowing is investigated. The governing partial differential equation and auxiliary conditions are converted to ordinary differential equations with the corresponding auxiliary conditions via Lie group analysis. The boundary layer temperature, concentration and nanoparticle volume fraction profiles are then determined numerically. The influences of various relevant parameters, namely, thermophoresis parameter Nt, Brownian motion parameter Nb, Lewis number Le, suction/injection parameter S, permeability parameter k 1 , source/sink parameter λ and Prandtl parameter Pr on temperature and concentration as well as wall heat flux and wall mass flux are discussed. Comparison with published results is presented.