The present review tries to give a general overview of the available information on cactus seed germination. First, information about the family Cactaceae is discussed, concerning aspects such as distribution and general characteristics. Seed distinctive features are mentioned, such as colour, form, and size. Aspects of seed physiology, such as germination and dormancy, as well as seed dynamics including dispersal, predation, and soil seed bank formation, are included in the discussion. Techniques of propagation and some aspects of longevity and conservation are mentioned. The areas where there is scarce information available are highlighted, and, therefore, are important areas in which to continue research in order to generate data for immediate and future conservation efforts.