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In the present study, we report that somatostatin receptor 2 (SSTR2) plays a crucial role in modulation of β 1 AR and β 2 AR mediated signaling pathways that are associated with increased intracellular Ca 2+ and cardiac complications. In H9c2 cells, SSTR2 colocalizes with β 1 AR or β 2 AR in receptor specific manner. SSTR2 selective agonist inhibits isoproterenol...
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