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Background The drug management of chronic urticaria can be divided into three approaches: (i) blockade of released histamine at the receptor sites; (ii) blockade of histamine release from mast cells; and (iii) blockade of other mediators and possible inflammatory and cellular components. The first approach is the most successful and widely used. It primarily involves the use of H 1 -antihistamines,...
Autoimmune progesterone dermatitis is a rarely recognized cutaneous disorder revealed by recurrent and cyclic skin eruption with variable morphology, during the luteal phase. We report the case of a 42-year-old woman with chronic urticaria since the age of 38 with premenstrual exacerbation. Intradermal progesterone tests revealed a strong reactivity against this hormone. Treatment with thalidomide...
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