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To evaluate the effectiveness of early and prolonged locomotor treatment with the use of a robotic-assisted gait training (RAGT) device (Lokomat; Hocoma Inc., Zurich, Switzerland) on the functional outcomes of patients after subacute stroke.A nonblinded prospective, randomized, controlled study.Rehabilitation department in tertiary university medical center.Sixty-seven patients in the first 3 months...
To determine the utility of the active straight leg raise (ASLR) test as a screen of lumbar spine stability and abdominal bracing (AB) ability.A biomechanical study of the ASLR test as a clinical evaluation of lumbar spine stability and AB.Clinical research laboratory.Fourteen participants who were currently asymptomatic for back pain and leg pain were evaluated.Spine posture, muscle activation, and...
Multipotent cells that can give rise to bone, cartilage, fat, connective tissue, and skeletal and cardiac muscle are termed mesenchymal stem cells. These cells were first identified in the bone marrow, distinct from blood-forming stem cells. Based on the embryologic derivation, availability, and various pro-regenerative characteristics, research exploring their use in cell therapy shows great promise...
To objectively evaluate the effect of ankle foot orthotics (AFOs) on functional ambulation in individuals with hemiplegia secondary to stroke using quantifiable outcome measures.With-without repeated measures design.Rehabilitation research center.Eighteen adults with stroke-related hemiplegia 6 months using a prescribed AFO.Not applicable.The distance (m) and velocity (m/s) during the 6-Minute Walk...
Physical exercise has been shown to play an ever-broadening role in the maintenance of overall health and has been implicated in the preservation of cognitive function in both healthy elderly and demented populations. Animal and human studies of acquired brain injury (ABI) from trauma or vascular causes also suggest a possible role for physical exercise in enhancing cognitive recovery.A review of...
To examine serum markers of matrix turnover in an animal model of disk degeneration.Randomized prospective in vivo study.Laboratory for Orthopaedic and Spine Research and Department of Large Animal Research.Twenty-one New Zealand White rabbits.Rabbits were randomly grouped into control (n = 8), sham surgery (n = 5), or stab surgery (n = 8). The stab surgical group underwent annulotomy of L2-3, L3-4,...
To determine whether posterior lumbar disk contour dimensions differ in the flexed seated, upright seated, and extended seated positions.Two subgroups of subjects with degenerative disk disease were compared: those with central posterior disk bulge (at L4-5 or L5-S1 levels) and those with a dark nucleus pulposus without posterior disk bulge (L3-4, L4-5, and/or L5-S1 levels).Academic medical center...
To determine whether digital subtraction angiography (DSA) combined with real-time fluoroscopic imaging improves the detection rate of intravascular injection during cervical transforaminal epidural steroid injections (CTFESIs).Retrospective analysis.Outpatient surgery center.A total of 134 subjects with cervical radicular pain who had CTFESIs performed by a single physician between June 9, 2004,...
To determine if self-reported levels of physical activity and fatigue are related to peak oxygen uptake (VO 2peak ) and whether these relationships differ among the patient groups (rheumatoid arthritis [RA], polymyositis [PM], and chronic fatigue syndrome [CFS]).Correlational investigation.Two ambulatory research clinics at the National Institutes of Health, Clinical Center, Bethesda, MD.There...
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