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Purpose. To evaluate visual function in rats with chronic elevation of intraocular pressure (IOP).Methods. Chronic ocular hypertension was induced in the left eye of 14 adult Brown Norway rats by cauterizing 3 vortex veins and 2 major episcleral veins; the right eye served as a non-operated control. A control group (n=5) was sham operated on the left eye. Prior to surgery, the IOP was measured with...
To determine whether the localization of retinal glutamate transporters is affected by retinal ischaemia and whether their ability to transport glutamate decreases with the progression of ischemic retinal and optic nerve degeneration.Retinal ischemia was induced in rats by acutely increasing the intraocular pressure (IOP, 110mmHg/60min). Reperfusion was permitted for periods up to 60 days post-ischemia...
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