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Preclinical research points to a strong modulatory influence of gonadal hormones on the serotonin system. However, human data corroborating this association remains scarce. The aim of this study was to examine the effects of hormone replacement therapy on 5-HT 1A receptor binding in postmenopausal women using positron emission tomography (PET) and the radioligand [carbonyl- 11 C]WAY-100635...
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