In this letter, we share our concerns regarding fluctuations of homozygosity for ApoE/ɛ4 allele. It appeared that over time, expression of this gene raised the felled as reported by various researchers. Considering the diversity of phenotypic characteristics assigned to expression of ApoE/ɛ4, seems to be a potentially useful to direct practitioner on concrete figures related to the genetic propensity of many conditions, from circulatory to mental disorders.
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