Cytokines regulate the immune reactions elicited by renal transplantation (RT). This study was designed to investigate the blood serum levels of IL-2, IL-6, IL-8 in 25 RT patients (10 female and 15 male, mean 5.4±2.7 yrs after RT) three times over a six-month period during standard immunosuppressive therapy with cyclosporine A, azathioprine and prednisolone. The levels of IL-2, IL-6 and IL-8 were tested with ELISA Quantikine Human Interleukin Immunoassay (R&D Systems, detection level 7,0.7 and 10 pg/cm3, respectively). There was no significant alternation of blood serum levels of IL-2, IL-6 and IL-8 in the study patients.
 Rysz J., Banach M., Ciałkowska-Rysz A., Stolarek R., Drozdz J., Okoński P., Blood serum levels of IL-2, IL-6, IL-8, TNF-a and IL-1b in patients on maintenance hemodialysis, Cell. Mol. Immunol., 2006, 3, 151–154
 Descamps-Latscha B., Herbelin A., Nguyen A.T., Roux-Lombard P., Zingraff J., Moynot A., et al., Balance between IL-1b, TNF-a, and their specific inhibitors in chronic renal failure and maintenance dialysis, J. Immunol., 1995, 154, 882–892
Financed by the National Centre for Research and Development under grant No. SP/I/1/77065/10 by the strategic scientific research and experimental development program:
SYNAT - “Interdisciplinary System for Interactive Scientific and Scientific-Technical Information”.