Ibuprofen membrane electrodes based on different plasticizers: diisobutyl phthalate (DIBP), o-nitrophenyloctyl ether (o-NPOE), dioctyl sebacate (DOS) and tetraoctylammonium 2-(4-isobutylphenyl)propionate were prepared. All electrodes show: a near Nernstian slope of characteristic (58.3–60.9 mV decade−1) in the measurement range (10−4–10−1 mol L−1), limit of detection (5.0×10−5 mol L−1), really long lifetime (12 months), dependence of the electrode potential on pH (5.5–9.0), reproducibility of potential (0.6–1.2 mV) and selectivity coefficients in relation to some organic and inorganic anions. The electrodes were applied for the determination of ibuprofen in tablets by the calibration curve method and the standard addition method. <alternatives> [...] </alternatives>
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