To observe a therapeutic effect of macrolide antibiotics in children with Pseudomonas aeruginosa pneumonia. Fifty-four cases of children with Pseudomonas aeruginosa pneumonia were randomly divided into an observation group (n=30) and a control group (n=24). The observation group was treated with macrolide antibiotics and cefoperazone/sulbactam. The control group was treated with cefoperazone/ sulbactam during a course of 10-14 days. The total effective rate was 93.3% in the observation group, and 58.3% in the control group, and results in the observation group were superior to the control group notably (P>0.05). There were no significant differences in bacterial clearance rate, adverse reaction rate between two groups (P>0.05). The combined application of cefoperazone/sulbactam with macrolide antibiotics to treat Pseudomonas aeruginosa pneumonia in children would be a more effective clinical method.
 Fujitani S., Sun H., Victor L., Pneumonia due to Pseudomonas aeruginosa, CHEST, 2011, 139(4), 909-919
 Fu W., Demei Z., Fupin H., et al., 2012 CHINET surveillance of bacterial resistance in China, Chinese Journal of Infection and Chemotherapy, 2013, 13(5), 321-330
 Hongbing C., Chunjiang Z., Hui W., et al., The common pathogens resistance analysis of nosocomial infections in 13 teaching hospitals in china in 2011, Chinese Journal of Internal Medicine, 2013, 52(3), 203-212
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