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Effects of lidocaine-HCl salt and benzocaine on the expansion of lipid monolayers employed as bio-mimicking cell membrane were investigated using Langmuir-Blodgett film balance to figure out the molecular mechanism for anesthesia by these local anesthetics. Lidocaine-HCl salt in subphase expanded the monolayer of phosphatidyl choline (PC) and phosphatidyl ethanolamine (PE). Benzocaine was not mixed...
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