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There is growing evidence of the health benefits of physical activity for young people, including reduced risk of obesity and improved psychological wellbeing. Conversely, sedentary behaviour is now recognised to increase the risk of later poor health. Patterns of physical activity and sedentary behaviour are established in early childhood. In July, 2011, the UK Chief Medical Officers released new...
Vitamin D was used to treat tuberculosis in the pre-antibiotic era, and its metabolites induce antimycobacterial immunity in vitro. Clinical trials investigating the effect of adjunctive vitamin D on sputum culture conversion are absent. We undertook a multicentre randomised controlled trial of adjunctive vitamin D in adults with sputum smear-positive pulmonary tuberculosis in London, UK. 146 patients...
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