Greg T. Blakney

article

Front-End Electron Transfer Dissociation Coupled to a 21 Tesla FT-ICR Mass Spectrometer for Intact Protein Sequence Analysis

Chad R. Weisbrod, Nathan K. Kaiser, John E. P. Syka, Lee Early, more

Journal of The American Society for Mass Spectrometry > 2017 > 28 > 9 > 1787-1795

High resolution mass spectrometry is a key technology for in-depth protein characterization. High-field Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) enables high-level interrogation of intact proteins in the most detail to date. However, an appropriate complement of fragmentation technologies must be paired with FTMS to provide comprehensive sequence coverage, as well as...

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21 Tesla Fourier Transform Ion Cyclotron Resonance Mass Spectrometer: A National Resource for Ultrahigh Resolution Mass Analysis

Christopher L. Hendrickson, John P. Quinn, Nathan K. Kaiser, Donald F. Smith, more

Journal of The American Society for Mass Spectrometry > 2015 > 26 > 9 > 1626-1632

We describe the design and initial performance of the first 21 tesla Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometer. The 21 tesla magnet is the highest field superconducting magnet ever used for FT-ICR and features high spatial homogeneity, high temporal stability, and negligible liquid helium consumption. The instrument includes a commercial dual linear quadrupole trap front...

article

Erratum to: Fourier Transform Ion Cyclotron Resonance Mass Resolution and Dynamic Range Limits Calculated by Computer Modeling of Ion Cloud Motion

Gleb Vladimirov, Christopher L. Hendrickson, Greg T. Blakney, Alan G. Marshall, more

Journal of The American Society for Mass Spectrometry > 2012 > 23 > 2 > 385-385

article

Fourier Transform Ion Cyclotron Resonance Mass Resolution and Dynamic Range Limits Calculated by Computer Modeling of Ion Cloud Motion

Gleb Vladimirov, Christopher L. Hendrickson, Greg T. Blakney, Alan G. Marshall, more

Journal of The American Society for Mass Spectrometry > 2012 > 23 > 2 > 375-384

Particle-in-Cell (PIC) ion trajectory calculations provide the most realistic simulation of Fourier transform ion cyclotron resonance (FT-ICR) experiments by efficient and accurate calculation of the forces acting on each ion in an ensemble (cloud), including Coulomb interactions (space charge), the electric field of the ICR trap electrodes, image charges on the trap electrodes, the magnetic field,...

article

Valence Parity to Distinguish c′ and z ^• Ions from Electron Capture Dissociation/Electron Transfer Dissociation of Peptides: Effects of Isomers, Isobars, and Proteolysis Specificity

Yuan Mao, Jeremiah D. Tipton, Greg T. Blakney, Christopher L. Hendrickson, more

Analytical Chemistry > 2011 > 83 > 20 > 8024 - 8028

article

Epitope Mapping of a 95 kDa Antigen in Complex with Antibody by Solution-Phase Amide Backbone Hydrogen/Deuterium Exchange Monitored by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

Qian Zhang, LeAnna N. Willison, Pallavi Tripathi, Shridhar K. Sathe, more

Analytical Chemistry > 2011 > 83 > 18 > 7129 - 7136

article

Predator data station: A fast data acquisition system for advanced FT-ICR MS experiments

Greg T. Blakney, Christopher L. Hendrickson, Alan G. Marshall

International Journal of Mass Spectrometry > 2011 > 306 > 2-3 > 246-252

Here, we present the Predator data station, a control system for FT-ICR mass spectrometers that champions speed and experimental flexibility while simultaneously providing stability, ease of use, and the ability to integrate more advanced hardware as it becomes available. The Predator is the first FT-ICR MS data station comprised solely of fast PCI, PXI, and yet faster PXI Express-based commercial...

article

Parts-Per-Billion Fourier Transform Ion Cyclotron Resonance Mass Measurement Accuracy with a “Walking” Calibration Equation

Joshua J. Savory, Nathan K. Kaiser, Amy M. McKenna, Feng Xian, more

Analytical Chemistry > 2011 > 83 > 5 > 1732 - 1736

article

Characterization of naphthenic acids in crude oils and naphthenates by electrospray ionization FT-ICR mass spectrometry

Mmilili M. Mapolelo, Ryan P. Rodgers, Greg T. Blakney, Andrew T. Yen, more

International Journal of Mass Spectrometry > 2011 > 300 > 2-3 > 149-157

We present the selective ionization of acidic components of crude oils and naphthenates by negative-ion electrospray ionization (ESI) Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). We further characterize isolated naphthenic acids from a calcium napthenate deposit by negative-ion ESI tandem mass spectrometry (MS ⁿ ): collision-induced dissociation (CID) and infrared...

article

Automated Broadband Phase Correction of Fourier Transform Ion Cyclotron Resonance Mass Spectra

Feng Xian, Christopher L. Hendrickson, Greg T. Blakney, Steven C. Beu, more

Analytical Chemistry > 2010 > 82 > 21 > 8807 - 8812

article

SIMION modeling of ion image charge detection in Fourier transform ion cyclotron resonance mass spectrometry

Christopher L. Hendrickson, Steven C. Beu, Greg T. Blakney, Alan G. Marshall

International Journal of Mass Spectrometry > 2009 > 283 > 1-3 > 100-104

We describe a novel SIMION model, based on the principle of reciprocity, to simulate ion–image charge detection and demonstrate utility for Fourier transform ion cyclotron resonance mass spectrometry. The model accommodates arbitrary electrode geometry, magnetic field inhomogeneity, ion-neutral collisions, and swept or single-frequency excitation, but does not account for ion–ion or ion–image charge...

article

Automated Electrospray Ionization FT-ICR Mass Spectrometry for Petroleum Analysis

Sunghwan Kim, Ryan P. Rodgers, Greg T. Blakney, Christopher L. Hendrickson, more

Journal of the American Society for Mass Spectrometry > 2009 > 20 > 2 > 263-268

Analysis of petroleum samples at the molecular level by Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) typically requires a prolonged accumulation of ions and/or summing up a large number of scans. Here, a chip-based micro-ESI system (Advion NanoMate, Ithaca, NY) has been successfully automated in combination with FT-ICR MS analysis of petroleum samples. A foil-sealed 96-well...

article

Automated electrospray ionization FT-ICR mass spectrometry for petroleum analysis

Sunghwan Kim, Ryan P. Rodgers, Greg T. Blakney, Christopher L. Hendrickson, more

Journal of The American Society for Mass Spectrometry > 2009 > 20 > 2 > 263-268

Analysis of petroleum samples at the molecular level by Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) typically requires a prolonged accumulation of ions and/or summing up a large number of scans. Here, a chip-based micro-ESI system (Advion NanoMate, Ithaca, NY) has been successfully automated in combination with FT-ICR MS analysis of petroleum samples. A foil-sealed 96-well...

article

Modification of Trapping Potential by Inverted Sidekick Electrode Voltage during Detection To Extend Time-Domain Signal Duration for Significantly Enhanced Fourier Transform Ion Cyclotron Resonance Mass Resolution

Sunghwan Kim, Myoung Choul Choi, Seungyoung Kim, Manhoi Hur, more

Analytical Chemistry > 2007 > 79 > 10 > 3575 - 3580

article

Multicomponent Internal Recalibration of an LC−FTICR-MS Analysis Employing a Partially Characterized Complex Peptide Mixture: Systematic and Random Errors

Corey M. Yanofsky, Alexander W. Bell, Souad Lesimple, Frank Morales, more

Analytical Chemistry > 2005 > 77 > 22 > 7246 - 7254

article

Broadband Phase Correction of FT-ICR Mass Spectra via Simultaneous Excitation and Detection

Steven C. Beu, Greg T. Blakney, John P. Quinn, Christopher L. Hendrickson, more

Analytical Chemistry > 2004 > 76 > 19 > 5756 - 5761

article

Liquid Chromatography−Fourier Transform Ion Cyclotron Resonance Mass Spectrometric Characterization of Protein Kinase C Phosphorylation

Michael J. Chalmers, John P. Quinn, Greg T. Blakney, Mark R. Emmett, more

Journal of Proteome Research > 2003 > 2 > 4 > 373 - 382

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Search results for: Greg T. Blakney

Front-End Electron Transfer Dissociation Coupled to a 21 Tesla FT-ICR Mass Spectrometer for Intact Protein Sequence Analysis

21 Tesla Fourier Transform Ion Cyclotron Resonance Mass Spectrometer: A National Resource for Ultrahigh Resolution Mass Analysis

Erratum to: Fourier Transform Ion Cyclotron Resonance Mass Resolution and Dynamic Range Limits Calculated by Computer Modeling of Ion Cloud Motion

Fourier Transform Ion Cyclotron Resonance Mass Resolution and Dynamic Range Limits Calculated by Computer Modeling of Ion Cloud Motion

Valence Parity to Distinguish c′ and z ^• Ions from Electron Capture Dissociation/Electron Transfer Dissociation of Peptides: Effects of Isomers, Isobars, and Proteolysis Specificity

Epitope Mapping of a 95 kDa Antigen in Complex with Antibody by Solution-Phase Amide Backbone Hydrogen/Deuterium Exchange Monitored by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

Predator data station: A fast data acquisition system for advanced FT-ICR MS experiments

Parts-Per-Billion Fourier Transform Ion Cyclotron Resonance Mass Measurement Accuracy with a “Walking” Calibration Equation

Characterization of naphthenic acids in crude oils and naphthenates by electrospray ionization FT-ICR mass spectrometry

Automated Broadband Phase Correction of Fourier Transform Ion Cyclotron Resonance Mass Spectra

SIMION modeling of ion image charge detection in Fourier transform ion cyclotron resonance mass spectrometry

Automated Electrospray Ionization FT-ICR Mass Spectrometry for Petroleum Analysis

Automated electrospray ionization FT-ICR mass spectrometry for petroleum analysis

Modification of Trapping Potential by Inverted Sidekick Electrode Voltage during Detection To Extend Time-Domain Signal Duration for Significantly Enhanced Fourier Transform Ion Cyclotron Resonance Mass Resolution

Multicomponent Internal Recalibration of an LC−FTICR-MS Analysis Employing a Partially Characterized Complex Peptide Mixture: Systematic and Random Errors

Broadband Phase Correction of FT-ICR Mass Spectra via Simultaneous Excitation and Detection

Liquid Chromatography−Fourier Transform Ion Cyclotron Resonance Mass Spectrometric Characterization of Protein Kinase C Phosphorylation

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