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Phthalates are widely used in industry as solvents, additives and plasticizers. Some phthalates and their monoester metabolites are known to cause carcinogenic, toxic or endocrine-modulating effects. Chorion tissues as human early embryo are the base of organogenesis. Embryo (3-8 weeks) is sensitive period of teratogensis. With the development of industrialization, in addition to genetic factors,...
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