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The aim of the study was to evaluate the type-1 immune response by analyzing T-bet expression in circulating T and B cells in Primary Progressive (PP) and Secondary Progressive (SP) Multiple Sclerosis (MS) patients. We found higher percentages of circulating CD4 + T-bet + and CD8 + T-bet + T cells in SPMS and PPMS than in remitting–relapsing MS patients and controls...
Regulatory CD4 + CD25 + Foxp3 + T cells are involved in the regulation of immune response and inhibit protective antitumor immunity. Celiac disease (CD), a food gluten–sensitive enteropathy, is considered a T-cell–mediated autoimmune disease and is generally associated with an overall increased risk of cancer in CD patients. We observed a higher percentage of circulating CD4...
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